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SNR10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 9164894, updated on 9-Dec-2024

Summary

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Official Symbol
SNR10
Primary source
SGD:S000007499
Locus tag
YNCG0013W
See related
AllianceGenome:SGD:S000007499
Gene type
ncRNA
RNA name
snoRNA
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables rRNA pseudouridylation guide activity. Involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA pseudouridine synthesis. Located in nucleolus. Part of box H/ACA snoRNP complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See SNR10 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (345986..346230)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Lif1p Neighboring gene Mf(Alpha)2p Neighboring gene uncharacterized protein Neighboring gene E2 ubiquitin-conjugating protein MMS2 Neighboring gene coiled-coil domain-containing protein MAD1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deletion of a yeast small nuclear RNA gene impairs growth. Tollervey D, et al. EMBO J, 1985 Dec 30. PMID 3004976, Free PMC Article
  2. Strong dependence between functional domains in a dual-function snoRNA infers coupling of rRNA processing and modification events. Liang XH, et al. Nucleic Acids Res, 2010 Jun. PMID 20144950, Free PMC Article
  3. SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs. Clark MW, et al. J Cell Biol, 1990 Nov. PMID 2121740, Free PMC Article
  4. High dosage of the small nucleolar RNA snR10 specifically suppresses defects of a yeast rrp5 mutant. Torchet C, et al. Mol Genet Genomics, 2002 Sep. PMID 12242501
  5. Rok1p is a putative RNA helicase required for rRNA processing. Venema J, et al. Mol Cell Biol, 1997 Jun. PMID 9154839, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • H/ACA box small nucleolar RNA (snoRNA); essential gene required for for preRNA processing, specifically for cleavage at sites A1 and A2; also guides pseudouridylation of large subunit (LSU) rRNA at position U2923

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables rRNA pseudouridylation guide activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of box H/ACA snoRNP complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleolus IPI
Inferred from Physical Interaction
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    345986..346230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_132179.1 RNA Sequence

    Status: REVIEWED

Gene LinkOut

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Molecular Biology Databases
Research Materials