NME1 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: NME1
Primary source: SGD:S000007436
Locus tag: YNCN0013W
See related: AllianceGenome:SGD:S000007436
Gene type: ncRNA
RNA name: RNase_MRP_RNA
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Contributes to ribonuclease MRP activity. Involved in mRNA processing; positive regulation of cell cycle; and rRNA processing. Part of ribonuclease MRP complex. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome XIV - NC_001146.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

RNA component of RNase MRP; RNase MRP cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; human ortholog is implicated in cartilage-hair hypoplasia (CHH)

Function	Evidence Code	Pubs
enables ribonuclease MRP activity	IEA Inferred from Electronic Annotation more info	PubMed
contributes_to ribonuclease MRP activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in mRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in rRNA processing	IDA Inferred from Direct Assay more info	PubMed
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in rRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of ribonuclease MRP complex	IDA Inferred from Direct Assay more info	PubMed
part_of ribonuclease MRP complex	IEA Inferred from Electronic Annotation more info	PubMed