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Pard3 par-3 family cell polarity regulator [ Mus musculus (house mouse) ]

Gene ID: 93742, updated on 27-Nov-2024

Summary

Official Symbol
Pard3provided by MGI
Official Full Name
par-3 family cell polarity regulatorprovided by MGI
Primary source
MGI:MGI:2135608
See related
Ensembl:ENSMUSG00000025812 AllianceGenome:MGI:2135608
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Asip; Par3; Phip; Par-3; Pard-3; Pard3a; D8Ertd580e
Summary
Predicted to enable identical protein binding activity; phosphatidylinositol phosphate binding activity; and protein phosphatase binding activity. Involved in several processes, including negative regulation of peptidyl-threonine phosphorylation; positive regulation of myelination; and positive regulation of receptor internalization. Acts upstream of or within several processes, including apical constriction; centrosome localization; and wound healing, spreading of cells. Located in several cellular components, including Schmidt-Lanterman incisure; internode region of axon; and lateral loop. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PARD3 (par-3 family cell polarity regulator). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Note: Par3 (Gene ID: 112235) and Pard3 (Gene ID: 93742) share the Par3 symbol/alias in common. Par3 is a widely used alternative name for par-3 family cell polarity regulator (Pard3), which can be confused with the official symbol for pulmonary adenoma resistance 3 (Par3). [13 May 2019]
Expression
Ubiquitous expression in ovary adult (RPKM 7.1), bladder adult (RPKM 6.3) and 28 other tissues See more
Orthologs
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Genomic context

See Pard3 in Genome Data Viewer
Location:
8 E2; 8 74.66 cM
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (127790131..128338767)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (127063381..127612286)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8275 Neighboring gene STARR-seq mESC enhancer starr_23085 Neighboring gene predicted gene, 38574 Neighboring gene GABA(A) receptor-associated protein like 2 pseudogene 8_1688.1 Neighboring gene STARR-seq mESC enhancer starr_23087 Neighboring gene STARR-seq mESC enhancer starr_23088 Neighboring gene STARR-seq mESC enhancer starr_23090 Neighboring gene STARR-positive B cell enhancer mm9_chr8:129965071-129965372 Neighboring gene predicted gene, 53207 Neighboring gene predicted gene 9909 Neighboring gene predicted gene, 51558 Neighboring gene predicted gene, 32478 Neighboring gene predicted gene, 32532

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (7)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylinositol-3,4,5-trisphosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-3,4,5-trisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables phosphatidylinositol-3-phosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-3-phosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables phosphatidylinositol-4,5-bisphosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-4,5-bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apical constriction IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in bicellular tight junction assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in bicellular tight junction assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell-cell adhesion IC
Inferred by Curator
more info
PubMed 
acts_upstream_of_or_within centrosome localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in establishment of centrosome localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in establishment of epithelial cell polarity ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of epithelial cell polarity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in establishment or maintenance of cell polarity TAS
Traceable Author Statement
more info
PubMed 
involved_in establishment or maintenance of epithelial cell apical/basal polarity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in establishment or maintenance of epithelial cell apical/basal polarity ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within microtubule cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in myelination in peripheral nervous system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of peptidyl-threonine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of receptor internalization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein targeting to membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in protein targeting to membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within regulation of actin filament-based process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of cellular localization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within wound healing, spreading of cells IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of PAR polarity complex ISO
Inferred from Sequence Orthology
more info
 
located_in Schmidt-Lanterman incisure IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in apical junction complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in apical junction complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in axonal growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in bicellular tight junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
located_in bicellular tight junction ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 
located_in cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell-cell junction ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 
located_in internode region of axon IDA
Inferred from Direct Assay
more info
PubMed 
located_in lateral loop IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in spindle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
partitioning defective 3 homolog
Names
atypical PKC isotype-specific-interacting protein
ephrin-interacting protein
par-3 (partitioning defective 3) homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013580.4NP_001013598.1  partitioning defective 3 homolog isoform 2

    See identical proteins and their annotated locations for NP_001013598.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2, also called PAR-3o2) differs in the 5' and 3' UTR and has multiple coding region differences compared to variant 5. These differences cause translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus and shorter and distinct C-terminus compared to isoform 5.
    Source sequence(s)
    AC105981, AC132321
    Consensus CDS
    CCDS40523.1
    UniProtKB/TrEMBL
    Q8BPQ6
    Related
    ENSMUSP00000125612.2, ENSMUST00000160717.8
    Conserved Domains (1) summary
    cd00992
    Location:330409
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  2. NM_001013581.3NP_001013599.1  partitioning defective 3 homolog isoform 1

    See identical proteins and their annotated locations for NP_001013599.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, also called PAR-3o1) differs in the 5' and 3' UTR and has multiple coding region differences compared to variant 5. These differences cause translation initiation at a downstream AUG and an isoform (1) with a shorter N-terminus and shorter and distinct C-terminus compared to isoform 5.
    Source sequence(s)
    AC105981, AC132321
    Consensus CDS
    CCDS22789.1
    UniProtKB/TrEMBL
    A0A0R4J1Y4, E0CZE2
    Related
    ENSMUSP00000124162.2, ENSMUST00000162456.8
    Conserved Domains (1) summary
    cd00992
    Location:330409
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  3. NM_001122850.2NP_001116322.1  partitioning defective 3 homolog isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 3' UTR and coding region compared to variant 5. The resulting isoform (4) has a shorter and distinct C-terminus compared to isoform 5.
    Source sequence(s)
    AC105981, AC132321, AC155818, AC165964
    Consensus CDS
    CCDS52712.1
    UniProtKB/TrEMBL
    E9PYJ2, Q8BPQ4
    Related
    ENSMUSP00000124319.2, ENSMUST00000162907.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)
  4. NM_001309391.1NP_001296320.1  partitioning defective 3 homolog isoform 5

    See identical proteins and their annotated locations for NP_001296320.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) encodes isoform 5.
    Source sequence(s)
    BC090616
    Consensus CDS
    CCDS80945.1
    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    UniProtKB/TrEMBL
    A5D6P2
    Related
    ENSMUSP00000125453.2, ENSMUST00000160272.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)
  5. NM_001309392.1NP_001296321.1  partitioning defective 3 homolog isoform 6

    See identical proteins and their annotated locations for NP_001296321.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an in-frame exon in the central coding region, compared to variant 5. The encoded isoform (6) is shorter than isoform 5.
    Source sequence(s)
    BC090616
    Consensus CDS
    CCDS80946.1
    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    UniProtKB/TrEMBL
    B7ZNY3
    Related
    ENSMUSP00000026921.7, ENSMUST00000026921.13
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)
  6. NM_001363431.1NP_001350360.1  partitioning defective 3 homolog isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (7) has the same N- and C-termini but is shorter compared to isoform 5.
    Source sequence(s)
    AC102819, AC105981, AC132321, AC155818, AC165964
    UniProtKB/TrEMBL
    B2RUK1, F6S7Z1
    Related
    ENSMUSP00000124718.2, ENSMUST00000162665.8
    Conserved Domains (3) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06495
    Location:11171187
    Transformer; Fruit fly transformer protein
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)
  7. NM_001363432.1NP_001350361.1  partitioning defective 3 homolog isoform 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) represents the longest transcript and encodes the longest isoform (8).
    Source sequence(s)
    AC102819, AC105981, AC132321, AC155818, AC165964
    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)
  8. NM_033620.2NP_296369.2  partitioning defective 3 homolog isoform 3

    See identical proteins and their annotated locations for NP_296369.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, compared to variant 5. The encoded isoform (3) is shorter than isoform 5.
    Source sequence(s)
    BC090616
    Consensus CDS
    CCDS22788.1
    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    UniProtKB/TrEMBL
    G3XA13
    Related
    ENSMUSP00000124282.2, ENSMUST00000162309.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1146
    DUF3534; Domain of unknown function (DUF3534)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    127790131..128338767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531520.3XP_006531583.1  partitioning defective 3 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  2. XM_006531523.3XP_006531586.1  partitioning defective 3 homolog isoform X2

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  3. XM_006531524.3XP_006531587.1  partitioning defective 3 homolog isoform X3

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  4. XM_006531527.3XP_006531590.1  partitioning defective 3 homolog isoform X5

    UniProtKB/TrEMBL
    F6S7Z1
    Conserved Domains (3) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06495
    Location:11201190
    Transformer; Fruit fly transformer protein
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  5. XM_006531529.3XP_006531592.1  partitioning defective 3 homolog isoform X10

    UniProtKB/TrEMBL
    E0CZE2
    Related
    ENSMUSP00000125450.2, ENSMUST00000162602.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  6. XM_006531530.3XP_006531593.1  partitioning defective 3 homolog isoform X11

    UniProtKB/TrEMBL
    E0CZE2
    Related
    ENSMUSP00000124934.2, ENSMUST00000159537.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  7. XM_030243870.1XP_030099730.1  partitioning defective 3 homolog isoform X13

    UniProtKB/TrEMBL
    E0CXR8
    Related
    ENSMUSP00000124141.2, ENSMUST00000160581.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  8. XM_006531532.3XP_006531595.1  partitioning defective 3 homolog isoform X14

    UniProtKB/TrEMBL
    E0CXR8
    Related
    ENSMUSP00000125064.2, ENSMUST00000161355.8
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  9. XM_006531531.3XP_006531594.1  partitioning defective 3 homolog isoform X12

    UniProtKB/TrEMBL
    E0CZE2
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  10. XM_006531533.3XP_006531596.1  partitioning defective 3 homolog isoform X15

    UniProtKB/TrEMBL
    Q8BPQ4
    Conserved Domains (2) summary
    cd00992
    Location:465544
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  11. XM_006531526.3XP_006531589.1  partitioning defective 3 homolog isoform X4

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  12. XM_030243868.1XP_030099728.1  partitioning defective 3 homolog isoform X8

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  13. XM_030243867.1XP_030099727.1  partitioning defective 3 homolog isoform X6

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  14. XM_030243869.1XP_030099729.1  partitioning defective 3 homolog isoform X9

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  15. XM_036154397.1XP_036010290.1  partitioning defective 3 homolog isoform X7

    UniProtKB/Swiss-Prot
    Q58T10, Q58T11, Q8CB21, Q99NH2
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  16. XM_030243872.1XP_030099732.1  partitioning defective 3 homolog isoform X17

    UniProtKB/TrEMBL
    Q8BPQ4
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins
  17. XM_030243871.1XP_030099731.1  partitioning defective 3 homolog isoform X16

    UniProtKB/TrEMBL
    Q8BPQ4
    Conserved Domains (2) summary
    cd00992
    Location:437516
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:283
    DUF3534; N-terminal of Par3 and HAL proteins