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dpb3 DNA polymerase epsilon Dpb3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 9406966, updated on 18-Sep-2024

Summary

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Official Symbol
dpb3
Official Full Name
DNA polymerase epsilon Dpb3
Primary source
PomBase:SPCC16C4.22
Locus tag
SPOM_SPCC16C4.22
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See dpb3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (684677..685496)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Dis3L2-like 3'-5'-exoribonuclease Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 6-phosphogluconolactonase Neighboring gene cyclin-dependent protein kinase Pho85/PhoA-like Pef1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Coordination of histone chaperones for parental histone segregation and epigenetic inheritance. Fang Y, et al. Genes Dev, 2024 Mar 22. PMID 38479839, Free PMC Article
  2. Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex. He H, et al. Proc Natl Acad Sci U S A, 2017 Nov 21. PMID 29109278, Free PMC Article
  3. DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast. Handa T, et al. Mol Biol Cell, 2012 Aug. PMID 22718908, Free PMC Article
  4. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to DNA polymerase processivity factor activity ISO
Inferred from Sequence Orthology
more info
  
enables nucleosome binding EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in CMG complex assembly IC
Inferred by Curator
more info
  
involved_in DNA replication-dependent chromatin assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in DNA strand elongation involved in mitotic DNA replication IC
Inferred by Curator
more info
 PubMed 
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic DNA replication initiation IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of epsilon DNA polymerase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in nuclear replication fork IC
Inferred by Curator
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DNA polymerase epsilon Dpb3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    684677..685496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355889.2 → NP_001343092.1  DNA polymerase epsilon Dpb3 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    C6Y4D0
    Conserved Domains (1) summary
    cl28542
    Location:10 → 86
    BUR6; Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog) [Transcription]
Nucleotide Protein
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