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lspA lipoprotein signal peptidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944800, updated on 3-Dec-2024

Summary

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Official Symbol
lspA
Official Full Name
lipoprotein signal peptidase
Primary source
ECOCYC:EG10548
Locus tag
b0027
See related
ASAP:ABE-0000096
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0028; lsp
Summary
The lspA gene encodes prolipoprotein signal peptidase (signal peptidase II) . [More information is available at EcoCyc: EG10548].
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Genomic context

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Sequence:
NC_000913.3 (25207..25701)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene bifunctional riboflavin kinase/FMN adenylyltransferase Neighboring gene isoleucine--tRNA ligase Neighboring gene peptidyl-prolyl cis-trans isomerase FkpB Neighboring gene 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An alternate pathway for the processing of the prolipoprotein signal peptide in Escherichia coli. Ghrayeb J, et al. J Biol Chem, 1985 Sep 15. PMID 2993296
  2. Rapid assay and purification of a unique signal peptidase that processes the prolipoprotein from Escherichia coli B. Dev IK, et al. J Biol Chem, 1984 Sep 10. PMID 6381496
  3. A distinct signal peptidase for prolipoprotein in Escherichia coli. Tokunaga M, et al. J Cell Biochem, 1984. PMID 6373799
  4. Prolipoprotein modification and processing enzymes in Escherichia coli. Tokunaga M, et al. J Biol Chem, 1984 Mar 25. PMID 6368552
  5. Temperature-sensitive prolipoprotein signal peptidase in an Escherichia coli mutant: use of the mutant for an efficient and convenient assay system. Yamagata H. J Biochem, 1983 Jun. PMID 6350278

See all (60) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables endopeptidase activity EXP
Inferred from Experiment
more info
 PubMed 
enables endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables endopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
lipoprotein signal peptidase
NP_414568.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    25207..25701
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414568.1 lipoprotein signal peptidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414568.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7RDY7
    Conserved Domains (1) summary
    PRK00376
    Location:2 → 160
    lspA; lipoprotein signal peptidase
Nucleotide Protein
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