bcr multidrug efflux pump Bcr [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: bcr
Official Full Name: multidrug efflux pump Bcr
Primary source: ECOCYC:EG11419
Locus tag: b2182
See related: ASAP:ABE-0007221
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: bicA; bicR; ECK2176; sur; suxA
Summary: EvgAS regulon. [More information is available at EcoGene: EG11419]. Bcr is a probable multidrug efflux protein, expression of which has been shown to confer resistance to bicyclomycin and sulfathiazole . [More information is available at EcoCyc: EG11419].
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NC_000913.3 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables cysteine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables dipeptide transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables sodium:proton antiporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables xenobiotic transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cysteine export across plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in dipeptide transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in peptide transport	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in response to antibiotic	IEA Inferred from Electronic Annotation more info
involved_in sodium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane	IEA Inferred from Electronic Annotation more info
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISM Inferred from Sequence Model more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain