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yajR putative transport protein YajR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945058, updated on 3-Dec-2024

Summary

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Official Symbol
yajR
Official Full Name
putative transport protein YajR
Primary source
ECOCYC:G6241
Locus tag
b0427
See related
ASAP:ABE-0001481
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0421
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13614]. The YajR protein is an uncharacterised member of the major facilitator superfamily (MFS) of transporters . [More information is available at EcoCyc: G6241].
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Genomic context

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Sequence:
NC_000913.3 (445302..446666, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein/nucleic acid deglycase 3 Neighboring gene 2-dehydropantoate 2-reductase Neighboring gene nucleotide binding protein YajQ Neighboring gene heme O synthase Neighboring gene cytochrome bo3 subunit 4 Neighboring gene cytochrome bo3 subunit 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A. Jiang D, et al. Proc Natl Acad Sci U S A, 2013 Sep 3. PMID 23950222, Free PMC Article
  2. Analysis of a complete library of putative drug transporter genes in Escherichia coli. Nishino K, et al. J Bacteriol, 2001 Oct. PMID 11566977, Free PMC Article
  3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
  4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
  5. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
putative transport protein YajR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    445302..446666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414961.4 putative transport protein YajR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414961.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3JLI0
    Conserved Domains (1) summary
    cd17472
    Location:17 → 389
    MFS_YajR_like; Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily
Nucleotide Protein
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