U.S. flag

An official website of the United States government

acrB multidrug efflux pump RND permease AcrB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945108, updated on 3-Dec-2024

Summary

Official Symbol
acrB
Official Full Name
multidrug efflux pump RND permease AcrB
Primary source
ECOCYC:EG11704
Locus tag
b0462
See related
ASAP:ABE-0001601
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
acrE; ECK0456
Summary
acrB is an acrF paralog. [More information is available at EcoGene: EG11704]. AcrB is an RND-type inner-membrane associate proton-substrate antiporter. [More information is available at EcoCyc: EG11704].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (481254..484403, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hemolysin expression-modulating protein Hha Neighboring gene Hha toxicity modulator TomB Neighboring gene multidrug efflux pump membrane fusion lipoprotein AcrA Neighboring gene DNA-binding transcriptional repressor AcrR

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by EcoCyc

Component Evidence Code Pubs
part_of efflux pump complex PubMed 
part_of efflux pump complex PubMed 
located_in membrane PubMed 
located_in membrane  
located_in periplasmic side of plasma membrane PubMed 
is_active_in plasma membrane  
located_in plasma membrane PubMed 
located_in plasma membrane  
located_in plasma membrane PubMed 

General protein information

Preferred Names
multidrug efflux pump RND permease AcrB

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    481254..484403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414995.1 multidrug efflux pump RND permease AcrB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414995.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A895P5Q3
    Conserved Domains (1) summary
    PRK15127
    Location:1 → 1049
    PRK15127; multidrug efflux RND transporter permease subunit AcrB
External link. Please review our privacy policy.