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cobC putative adenosylcobalamin phosphatase/alpha-ribazole phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945246, updated on 3-Dec-2024

Summary

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Official Symbol
cobC
Official Full Name
putative adenosylcobalamin phosphatase/alpha-ribazole phosphatase
Primary source
ECOCYC:G6349
Locus tag
b0638
See related
ASAP:ABE-0002185
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0631; phpB
Summary
Primarily characterized in Salmonella. [More information is available at EcoGene: EG13240]. In Salmonella typhimurium, the cobC gene encodes the -ribazole-5'-P phosphatase in the cobalamin biosynthetic pathway . [More information is available at EcoCyc: G6349].
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Genomic context

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Sequence:
NC_000913.3 (669296..669907, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 23S rRNA m(3)psi1915 methyltransferase Neighboring gene ribosomal silencing factor RsfS Neighboring gene nicotinate-nucleotide adenylyltransferase Neighboring gene DNA polymerase III subunit delta Neighboring gene lipopolysaccharide assembly protein LptE

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The cobC gene of Salmonella typhimurium codes for a novel phosphatase involved in the assembly of the nucleotide loop of cobalamin. O'Toole GA, et al. J Biol Chem, 1994 Oct 21. PMID 7929373
  2. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  3. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503
  4. Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Riley M, et al. Nucleic Acids Res, 2006. PMID 16397293, Free PMC Article
  5. The histidine phosphatase superfamily: structure and function. Rigden DJ. Biochem J, 2008 Jan 15. PMID 18092946

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-ribazole phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cobalamin biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative adenosylcobalamin phosphatase/alpha-ribazole phosphatase
NP_415171.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    669296..669907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415171.1 putative adenosylcobalamin phosphatase/alpha-ribazole phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415171.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3JKR0
    Conserved Domains (1) summary
    PRK15004
    Location:1 → 198
    PRK15004; adenosylcobalamin/alpha-ribazole phosphatase
Nucleotide Protein
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