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allR DNA-binding transcriptional repressor AllR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945333, updated on 3-Dec-2024

Summary

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Official Symbol
allR
Official Full Name
DNA-binding transcriptional repressor AllR
Primary source
ECOCYC:G6276
Locus tag
b0506
See related
ASAP:ABE-0001750
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0499; glxA3; ybbU
Summary
IclR family. [More information is available at EcoGene: EG13616].
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Genomic context

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Sequence:
NC_000913.3 (533011..533826)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator AllS Neighboring gene ureidoglycolate lyase Neighboring gene ncRNA Neighboring gene glyoxylate carboligase Neighboring gene hydroxypyruvate isomerase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR. Walker JR, et al. J Mol Biol, 2006 May 5. PMID 16546208
  2. Mass spectrometric study of the Escherichia coli repressor proteins, Ic1R and Gc1R, and their complexes with DNA. Donald LJ, et al. Protein Sci, 2001 Jul. PMID 11420439, Free PMC Article
  3. The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines. Hasegawa A, et al. Microbiology (Reading), 2008 Nov. PMID 18957590
  4. Regulation of the Escherichia coli allantoin regulon: coordinated function of the repressor AllR and the activator AllS. Rintoul MR, et al. J Mol Biol, 2002 Dec 6. PMID 12460564
  5. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AllR, together with AllS, plays a key role in switching control of two pathways, nitrogen assimilation and energy production.
    Title: The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines.
  2. glyoxylate was shown to conformationally change the AllR tetramer as well as monomer and dimer resulting in altered outline of AllR molecules
    Title: Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcriptional repressor AllR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    533011..533826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415039.1 DNA-binding transcriptional repressor AllR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415039.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6C9QDQ8
    Conserved Domains (1) summary
    PRK10163
    Location:1 → 271
    PRK10163; HTH-type transcriptional repressor AllR
Nucleotide Protein
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