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sodC superoxide dismutase (Cu-Zn) [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945343, updated on 3-Dec-2024

Summary

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Official Symbol
sodC
Official Full Name
superoxide dismutase (Cu-Zn)
Primary source
ECOCYC:G6886
Locus tag
b1646
See related
ASAP:ABE-0005505
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1642
Summary
SodC is repressed anaerobically by Fnr and is induced in stationary phase by RpoS. [More information is available at EcoGene: EG13419]. SodC is a periplasmic enzyme that converts superoxide radicals to hydrogen peroxide and water. [More information is available at EcoCyc: G6886].
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Genomic context

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Sequence:
NC_000913.3 (1724134..1724655, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative membrane fusion protein YdhJ Neighboring gene putative transporter YdhK Neighboring gene putative oxidoreductase YdhF Neighboring gene DUF1289 domain-containing protein YdhL

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The regulation and role of the periplasmic copper, zinc superoxide dismutase of Escherichia coli. Gort AS, et al. Mol Microbiol, 1999 Apr. PMID 10216871
  2. Isolation of a new copper-containing superoxide dismutase bacteriocuprein. Puget K, et al. Biochem Biophys Res Commun, 1974 Jun 4. PMID 4836277
  3. Isolation of an active and heat-stable monomeric form of Cu,Zn superoxide dismutase from the periplasmic space of Escherichia coli. Battistoni A, et al. FEBS Lett, 1995 Oct 30. PMID 7589534
  4. Copper, zinc superoxide dismutase in Escherichia coli: periplasmic localization. Benov L, et al. Arch Biochem Biophys, 1995 Jun 1. PMID 7786035
  5. Escherichia coli expresses a copper- and zinc-containing superoxide dismutase. Benov LT, et al. J Biol Chem, 1994 Oct 14. PMID 7929223

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The role of the three SodCs is not redundant in biofilm formation and the resistance to oxidative damage.
    Title: A study on prophagic and chromosomal sodC genes involvement in Escherichia coli O157:H7 biofilm formation and biofilm resistance to H2O2.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables antioxidant activity IEA
Inferred from Electronic Annotation
more info
  
enables copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables copper ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables superoxide dismutase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables superoxide dismutase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in removal of superoxide radicals IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within superoxide metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
superoxide dismutase (Cu-Zn)
NP_416163.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1724134..1724655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416163.1 superoxide dismutase (Cu-Zn) [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416163.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1V2GBM9, A0A376LNG2, A0A7D7KFC7, B1AEH5
    Conserved Domains (1) summary
    PRK10290
    Location:1 → 173
    PRK10290; superoxide dismutase [Cu-Zn] SodC2
Nucleotide Protein
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