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roxA 50S ribosomal protein L16-arginine 3-hydroxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945391, updated on 17-Dec-2024

Summary

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Official Symbol
roxA
Official Full Name
50S ribosomal protein L16-arginine 3-hydroxylase
Primary source
ECOCYC:EG11430
Locus tag
b1128
See related
ASAP:ABE-0003802
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1114; ycfD
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Genomic context

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Sequence:
NC_000913.3 (1187119..1188240, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene spermidine preferential ABC transporter ATP binding subunit Neighboring gene peptidase T Neighboring gene sensor histidine kinase PhoQ Neighboring gene DNA-binding transcriptional dual regulator PhoP Neighboring gene adenylosuccinate lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular analysis of the Escherichia coli phoP-phoQ operon. Kasahara M, et al. J Bacteriol, 1992 Jan. PMID 1729240, Free PMC Article
  2. Identification and functional analysis of 'hypothetical' genes expressed in Haemophilus influenzae. Kolker E, et al. Nucleic Acids Res, 2004. PMID 15121896, Free PMC Article
  3. Structure and functional analysis of YcfD, a novel 2-oxoglutarate/Fe²⁺-dependent oxygenase involved in translational regulation in Escherichia coli. van Staalduinen LM, et al. J Mol Biol, 2014 May 1. PMID 24530688
  4. Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans. Ge W, et al. Nat Chem Biol, 2012 Dec. PMID 23103944, Free PMC Article
  5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The crystal structure of YcfD at 2.7 A resolution reveals that YcfD is structurally similar to known JmjC proteins and possesses the characteristic double-stranded beta-helix fold or cupin domain.
    Title: Structure and functional analysis of YcfD, a novel 2-oxoglutarate/Fe²⁺-dependent oxygenase involved in translational regulation in Escherichia coli.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-oxoglutarate-dependent dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2-oxoglutarate-dependent dioxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within post-translational protein modification IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
50S ribosomal protein L16-arginine 3-hydroxylase
NP_415646.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1187119..1188240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415646.4 50S ribosomal protein L16-arginine 3-hydroxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415646.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3JJK1, A0A829KYB2, B3Y0B7
    Conserved Domains (1) summary
    COG2850
    Location:1 → 373
    RoxA; Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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