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puuE 4-aminobutyrate aminotransferase PuuE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945446, updated on 3-Dec-2024

Summary

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Official Symbol
puuE
Official Full Name
4-aminobutyrate aminotransferase PuuE
Primary source
ECOCYC:G6646
Locus tag
b1302
See related
ASAP:ABE-0004380
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1297; goaG
Summary
PuuE was identified as a putrescine-inducible GABA aminotransferase, which allows cells to grow on putrescine as the sole source of nitrogen even in the absence of GabT . [More information is available at EcoCyc: G6646].
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Genomic context

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Sequence:
NC_000913.3 (1365550..1366815)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase Neighboring gene gamma-glutamylputrescine oxidase Neighboring gene DNA-binding transcriptional dual regulator PspF Neighboring gene phage shock protein A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spot 42 RNA regulates putrescine catabolism in Escherichia coli by controlling the expression of puuE at the post-transcription level. Sun X, et al. J Microbiol, 2021 Feb. PMID 33527317
  2. A putrescine-inducible pathway comprising PuuE-YneI in which gamma-aminobutyrate is degraded into succinate in Escherichia coli K-12. Kurihara S, et al. J Bacteriol, 2010 Sep. PMID 20639325, Free PMC Article
  3. The RIB element in the goaG-pspF intergenic region of Escherichia coli. Jovanovic G, et al. J Bacteriol, 1997 May. PMID 9150200, Free PMC Article
  4. A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12. Kurihara S, et al. J Biol Chem, 2005 Feb 11. PMID 15590624
  5. A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. Aiba H, et al. DNA Res, 1996 Dec 31. PMID 9097039

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Spot 42 RNA regulates putrescine catabolism in Escherichia coli by controlling the expression of puuE at the post-transcription level.
    Title: Spot 42 RNA regulates putrescine catabolism in Escherichia coli by controlling the expression of puuE at the post-transcription level.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4-aminobutyrate:2-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in gamma-aminobutyric acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gamma-aminobutyric acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within putrescine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
4-aminobutyrate aminotransferase PuuE
NP_415818.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1365550..1366815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415818.1 4-aminobutyrate aminotransferase PuuE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415818.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H9XUT6, A0A8T6PS95
    Conserved Domains (1) summary
    PRK09792
    Location:1 → 421
    PRK09792; 4-aminobutyrate transaminase; Provisional
Nucleotide Protein
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