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uxaB tagaturonate reductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945542, updated on 17-Dec-2024

Summary

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Official Symbol
uxaB
Official Full Name
tagaturonate reductase
Primary source
ECOCYC:EG11065
Locus tag
b1521
See related
ASAP:ABE-0005076
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1514
Summary
ExuR regulon. [More information is available at EcoGene: EG11065]. Altronate oxidoreductase is the second enzyme of the galacturonate catabolism pathway, catalyzing the reversible NADH-dependent reduction of D-tagaturonate to D-altronate . [More information is available at EcoCyc: EG11065].
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Genomic context

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Sequence:
NC_000913.3 (1609229..1610680, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene trans-aconitate 2-methyltransferase Neighboring gene PF01062 family inner membrane protein YneE Neighboring gene putative diguanylate cyclase DgcF Neighboring gene DUF4186 domain-containing protein YneG Neighboring gene glutaminase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determination of the transcription direction of the uxaB gene, in Escherichia coli K12. Hugouvieux-Cotte-Pattat N, et al. Mol Gen Genet, 1983. PMID 6343794
  2. [D-altronate: NAD-oxidoreductase in Escherichia coli K12. Purification, properties, and specificity]. Portalier RC, et al. Eur J Biochem, 1972 Mar 15. PMID 4402917
  3. [D-altronate: NAD-oxidoreductase from Escherichia coli K12. Kinetic studies]. Portalier RC. Eur J Biochem, 1972 Oct. PMID 4351434
  4. Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia coli. HICKMAN J, et al. J Biol Chem, 1960 Jun. PMID 14401695
  5. D-Mannonate and D-altronate-NAD dehydrogenases from Escherichia coli. Portalier R, et al. Methods Enzymol, 1982. PMID 6755169

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: A DNA sequence containing the control sites for the uxaB gene of Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables mannitol-1-phosphate 5-dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables tagaturonate reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tagaturonate reductase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tagaturonate reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-galacturonate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within D-galacturonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mannitol catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tagaturonate reductase
YP_025302.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1609229..1610680 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_025302.1 tagaturonate reductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_025302.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7KJY6
    Conserved Domains (1) summary
    PRK03643
    Location:1 → 472
    PRK03643; tagaturonate reductase
Nucleotide Protein
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