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ssuD FMNH2-dependent alkanesulfonate monooxygenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945557, updated on 3-Dec-2024

Summary

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Official Symbol
ssuD
Official Full Name
FMNH2-dependent alkanesulfonate monooxygenase
Primary source
ECOCYC:G6477
Locus tag
b0935
See related
ASAP:ABE-0003178
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0926; ssi6; ycbN
Summary
SsuD and SsuE form a stable complexand comprise a two-component alkanesulfonate monooxygenase system (Abdurachim, 2006). [More information is available at EcoGene: EG13706]. Escherichia coli can utilize alkanesulfonates as a sulfur source for growth. [More information is available at EcoCyc: G6477].
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Genomic context

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Sequence:
NC_000913.3 (994843..995988, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene aminopeptidase N Neighboring gene aliphatic sulfonate ABC transporter ATP binding subunit Neighboring gene aliphatic sulfonate ABC transporter membrane subunit Neighboring gene aliphatic sulfonate ABC transporter periplasmic binding protein Neighboring gene NADPH-dependent FMN reductase Neighboring gene putative laminin-binding fimbrial subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Escherichia coli utilizes methanesulfonate and L-cysteate as sole sulfur sources for growth. Eichhorn E, et al. FEMS Microbiol Lett, 2001 Dec 18. PMID 11750815
  2. Catalytic role of a conserved cysteine residue in the desulfonation reaction by the alkanesulfonate monooxygenase enzyme. Carpenter RA, et al. Biochim Biophys Acta, 2010 Jan. PMID 19770075
  3. Catalytic importance of the substrate binding order for the FMNH2-dependent alkanesulfonate monooxygenase enzyme. Zhan X, et al. Biochemistry, 2008 Feb 19. PMID 18198899
  4. Crystal structure of Escherichia coli alkanesulfonate monooxygenase SsuD. Eichhorn E, et al. J Mol Biol, 2002 Nov 29. PMID 12445781
  5. Detection of protein-protein interactions in the alkanesulfonate monooxygenase system from Escherichia coli. Abdurachim K, et al. J Bacteriol, 2006 Dec. PMID 16997955, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alkanesulfonate monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alkanesulfonate monooxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alkanesulfonate monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in alkanesulfonate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in alkanesulfonate catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within alkanesulfonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to sulfur starvation NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein homotetramerization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to heat IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of alkanesulfonate monooxygenase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of alkanesulfonate monooxygenase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
FMNH2-dependent alkanesulfonate monooxygenase
NP_415455.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    994843..995988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415455.1 FMNH2-dependent alkanesulfonate monooxygenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415455.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6PQD3
    Conserved Domains (1) summary
    PRK00719
    Location:3 → 380
    PRK00719; alkanesulfonate monooxygenase; Provisional
Nucleotide Protein
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