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nagK N-acetyl-D-glucosamine kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945664, updated on 3-Dec-2024

Summary

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Official Symbol
nagK
Official Full Name
N-acetyl-D-glucosamine kinase
Primary source
ECOCYC:G6576
Locus tag
b1119
See related
ASAP:ABE-0003778
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1105; ycfX
Summary
nagK is not an essential gene. [More information is available at EcoGene: EG13442]. N-acetyl-D-glucosamine (GlcNAc) is released in the cytoplasm during murein recycling. [More information is available at EcoCyc: G6576].
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Genomic context

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Sequence:
NC_000913.3 (1178593..1179504)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipoprotein release complex - inner membrane subunit Neighboring gene lipoprotein release complex - ATP binding subunit Neighboring gene lipoprotein release complex - inner membrane subunit Neighboring gene CobB-S;protein-lysine deacetylase/desuccinylase/lipoamidase Neighboring gene putative inner membrane protein YcfZ Neighboring gene putative inner membrane protein YmfA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling. Uehara T, et al. J Bacteriol, 2004 Nov. PMID 15489439, Free PMC Article
  2. Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases. Miller BG, et al. Biochemistry, 2004 Jun 1. PMID 15157072
  3. An alternative route for recycling of N-acetylglucosamine from peptidoglycan involves the N-acetylglucosamine phosphotransferase system in Escherichia coli. Plumbridge J. J Bacteriol, 2009 Sep. PMID 19617367, Free PMC Article
  4. How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Park JT, et al. Microbiol Mol Biol Rev, 2008 Jun. PMID 18535144, Free PMC Article
  5. Interaction network containing conserved and essential protein complexes in Escherichia coli. Butland G, et al. Nature, 2005 Feb 3. PMID 15690043

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables N-acetylglucosamine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetylglucosamine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables N-acetylglucosamine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within peptidoglycan turnover EXP
Inferred from Experiment
more info
 PubMed 
involved_in peptidoglycan turnover IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
N-acetyl-D-glucosamine kinase
NP_415637.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1178593..1179504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415637.1 N-acetyl-D-glucosamine kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415637.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376X2V2, A0A8T6PSL4
    Conserved Domains (1) summary
    PRK13310
    Location:1 → 303
    PRK13310; N-acetyl-D-glucosamine kinase; Provisional
Nucleotide Protein
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