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aroH 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946229, updated on 3-Dec-2024

Summary

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Official Symbol
aroH
Official Full Name
3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive
Primary source
ECOCYC:EG10080
Locus tag
b1704
See related
ASAP:ABE-0005686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1702
Summary
The aroH gene has two promoters. [More information is available at EcoCyc: EG10080].
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Genomic context

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Sequence:
NC_000913.3 (1788435..1789481)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoenolpyruvate synthetase Neighboring gene phosphoenolpyruvate synthetase regulatory protein Neighboring gene PF10636 family protein YdiE Neighboring gene protein adenylyltransferase SelO

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and properties of tryptophan-sensitive 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli. Ray JM, et al. J Bacteriol, 1991 Mar. PMID 1672127, Free PMC Article
  2. Purification and properties of 3-deoxy-D-arabionheptulosonic acid-7-phosphate synthetase (trp) from Escherichia coli. Camakaris J, et al. J Bacteriol, 1974 Nov. PMID 4218228, Free PMC Article
  3. Inhibition of 3-deoxy-d-arabinoheptulosonic acid-7-phosphate synthetase (trp) in Escherichia coli. Pittard J, et al. J Bacteriol, 1969 Mar. PMID 4887505, Free PMC Article
  4. Steady-state kinetics and inhibitor binding of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (tryptophan sensitive) from Escherichia coli. Akowski JP, et al. Biochemistry, 1997 Dec 16. PMID 9398312
  5. Repression of 3-deoxy-D-arabinoheptulosonic acid-7-phosphate synthetase (trp) and enzymes of the tryptophan pathway in Escherichia coli K-12. Camakaris J, et al. J Bacteriol, 1971 Aug. PMID 4939760, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-deoxy-7-phosphoheptulonate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-deoxy-7-phosphoheptulonate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 3-deoxy-7-phosphoheptulonate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid family biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within aromatic amino acid family biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in aromatic amino acid family biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in chorismate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive
NP_416219.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1788435..1789481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416219.1 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416219.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6C9QEW0
    Conserved Domains (1) summary
    PRK12756
    Location:1 → 348
    PRK12756; Trp-sensitive 3-deoxy-7-phosphoheptulonate synthase AroH
Nucleotide Protein
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