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lsrD Autoinducer-2 ABC transporter membrane subunit LsrD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946264, updated on 3-Dec-2024

Summary

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Official Symbol
lsrD
Official Full Name
Autoinducer-2 ABC transporter membrane subunit LsrD
Primary source
ECOCYC:G6802
Locus tag
b1515
See related
ASAP:ABE-0005061
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1508; ydeZ
Summary
LsrD is paralogous to ribose transport membrane channel protein RbsC and is in an operon regulated by LsrR and LuxS, through AI-2. [More information is available at EcoGene: EG13808]. LsrD is a membrane component of a predicted ATP-dependent sugar transporter. [More information is available at EcoCyc: G6802].
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Genomic context

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Sequence:
NC_000913.3 (1604047..1605039)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor LsrR Neighboring gene Autoinducer-2 ABC transporter ATP binding subunit Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrC Neighboring gene Autoinducer-2 ABC transporter periplasmic binding protein Neighboring gene 3-hydroxy-2,4-pentadione 5-phosphate thiolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Taga ME, et al. Mol Microbiol, 2001 Nov. PMID 11722742
  2. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. Xavier KB, et al. J Bacteriol, 2005 Jan. PMID 15601708, Free PMC Article
  3. Cyclic AMP (cAMP) and cAMP receptor protein influence both synthesis and uptake of extracellular autoinducer 2 in Escherichia coli. Wang L, et al. J Bacteriol, 2005 Mar. PMID 15743955, Free PMC Article
  4. Cell-to-cell signalling in Escherichia coli and Salmonella enterica. Ahmer BM. Mol Microbiol, 2004 May. PMID 15130116
  5. luxS-dependent gene regulation in Escherichia coli K-12 revealed by genomic expression profiling. Wang L, et al. J Bacteriol, 2005 Dec. PMID 16321939, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in autoinducer AI-2 transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in autoinducer AI-2 transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in quorum sensing NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Autoinducer-2 ABC transporter membrane subunit LsrD
NP_416032.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1604047..1605039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416032.1 Autoinducer-2 ABC transporter membrane subunit LsrD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416032.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YDF9, A0A8T6A379
    Conserved Domains (1) summary
    PRK15038
    Location:1 → 330
    PRK15038; autoinducer 2 ABC transporter permease LsrD
Nucleotide Protein
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