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insC3 IS2 insertion element repressor InsA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946455, updated on 17-Dec-2024

Summary

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Official Symbol
insC3
Official Full Name
IS2 insertion element repressor InsA
Primary source
ECOCYC:G7077
Locus tag
b1997
See related
ASAP:ABE-0006631
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0357; yi21-3
Summary
IS2E is a partial IS2 sequence and has insC deleted. [More information is available at EcoGene: EG60034]. InsA is a transcriptional repressor for the insertion element IS2. [More information is available at EcoCyc: G7077].
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Genomic context

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Sequence:
NC_000913.3 (2069815..2070180, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo Neighboring gene IS2 insertion element protein InsB Neighboring gene pseudo Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Negative regulation of IS2 transposition by the cyclic AMP (cAMP)-cAMP receptor protein complex. Hu ST, et al. J Bacteriol, 1998 May. PMID 9573153, Free PMC Article
  2. Functional domains of the InsA protein of IS2. Lei GS, et al. J Bacteriol, 1997 Oct. PMID 9335268, Free PMC Article
  3. Functional analysis of the 14 kDa protein of insertion sequence 2. Hu ST, et al. J Mol Biol, 1994 Feb 18. PMID 8107136
  4. Transcription initiation sites within an IS2 insertion in a Gal-constitutive mutant of Escherichia coli. Hinton DM, et al. Nucleic Acids Res, 1982 Aug 25. PMID 6291000, Free PMC Article
  5. IS2, a genetic element for turn-off and turn-on of gene activity in E. coli. Saedler H, et al. Mol Gen Genet, 1974. PMID 4610339

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transposase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA transposition IEA
Inferred from Electronic Annotation
more info
  
involved_in transposition IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
IS2 insertion element repressor InsA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2069815..2070180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026163.2 IS2 insertion element repressor InsA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026163.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0K5STT8, A0A2P9ELD4, A0A2X3BHA0, A0A2Y0AFV9, A0A376IUY9, A0A376J773, A0A376JW60, A0A376ZRC6, A0A377DG20, A0A377HC68, A0A446GLX8, A0A836N848, A0AAP7TKR5, A0AAQ1TAP0, B3Y0T5, F4SUN9
    Conserved Domains (1) summary
    PRK09413
    Location:1 → 121
    PRK09413; IS2 repressor TnpA; Reviewed
Nucleotide Protein
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