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hprR DNA-binding transcriptional dual regulator HprR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946486, updated on 3-Dec-2024

Summary

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Official Symbol
hprR
Official Full Name
DNA-binding transcriptional dual regulator HprR
Primary source
ECOCYC:G7057
Locus tag
b1969
See related
ASAP:ABE-0006533
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1965; yedW
Summary
Part of putative two-component regulator system with response regulator YedV. [More information is available at EcoGene: EG14045]. The yedW gene is predicted to encode a two-component response regulator . [More information is available at EcoCyc: G7057].
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Genomic context

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Sequence:
NC_000913.3 (2038152..2038823, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene protein/nucleic acid deglycase 1 Neighboring gene sensor histidine kinase HprS Neighboring gene hydroxyisourate hydrolase/transthyretin-related protein Neighboring gene protein-L-methionine sulfoxide reductase catalytic subunit MsrP

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding. Zorzini V, et al. Nucleic Acids Res, 2015 Jan. PMID 25564525, Free PMC Article
  2. Cooperative regulation of the common target genes between H₂O₂-sensing YedVW and Cu²⁺-sensing CusSR in Escherichia coli. Urano H, et al. Microbiology (Reading), 2015 Apr. PMID 25568260
  3. System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids. Gao R, et al. Mol Microbiol, 2008 Sep. PMID 18631241, Free PMC Article
  4. Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli. Hirakawa H, et al. J Antimicrob Chemother, 2003 Oct. PMID 12951338
  5. Transcriptional response of Escherichia coli to external copper. Yamamoto K, et al. Mol Microbiol, 2005 Apr. PMID 15773991

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphorelay response regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-DNA complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional dual regulator HprR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2038152..2038823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416478.2 DNA-binding transcriptional dual regulator HprR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416478.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3JL24, A0AAN3VA83, C3T4J2
    Conserved Domains (1) summary
    PRK11517
    Location:1 → 223
    PRK11517; DNA-binding response regulator HprR
Nucleotide Protein
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