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hprS sensor histidine kinase HprS [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946487, updated on 3-Dec-2024

Summary

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Official Symbol
hprS
Official Full Name
sensor histidine kinase HprS
Primary source
ECOCYC:G7056
Locus tag
b1968
See related
ASAP:ABE-0006531
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1964; yedV
Summary
[More information is available at EcoGene: EG14044]. YedV and YedW are predicted to function as a histidine kinase/response regulator pair of a two-component signal transduction system. [More information is available at EcoCyc: G7056].
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Genomic context

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Sequence:
NC_000913.3 (2036794..2038152, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene protein/nucleic acid deglycase 1 Neighboring gene DNA-binding transcriptional dual regulator HprR Neighboring gene hydroxyisourate hydrolase/transthyretin-related protein Neighboring gene protein-L-methionine sulfoxide reductase catalytic subunit MsrP

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HprSR Is a Reactive Chlorine Species-Sensing, Two-Component System in Escherichia coli. El Hajj S, et al. J Bacteriol, 2022 Feb 15. PMID 34898261, Free PMC Article
  2. Compilation of all genes encoding two-component phosphotransfer signal transducers in the genome of Escherichia coli. Mizuno T. DNA Res, 1997 Apr 28. PMID 9205844
  3. Transcriptional response of Escherichia coli to external copper. Yamamoto K, et al. Mol Microbiol, 2005 Apr. PMID 15773991
  4. Phenotype microarray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems. Zhou L, et al. J Bacteriol, 2003 Aug. PMID 12897016, Free PMC Article
  5. Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12. Oshima T, et al. Mol Microbiol, 2002 Oct. PMID 12366850

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorelay sensor kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorelay sensor kinase activity RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity, transferring phosphorus-containing groups IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in phosphorelay signal transduction system IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in response to copper ion IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to hypochlorite IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in signal transduction RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
sensor histidine kinase HprS
NP_416477.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2036794..2038152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416477.1 sensor histidine kinase HprS [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416477.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7ELQ1, A0A8S7HZA5
    Conserved Domains (1) summary
    TIGR01386
    Location:3 → 449
    cztS_silS_copS; heavy metal sensor kinase
Nucleotide Protein
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