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mtfA Mlc titration factor [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946489, updated on 3-Dec-2024

Summary

Official Symbol
mtfA
Official Full Name
Mlc titration factor
Primary source
ECOCYC:G7063
Locus tag
b1976
See related
ASAP:ABE-0006558
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1972; yeeI
Summary
An mtfA mutation has elevated ptsG activity; overproduction increases pstG and dgsA(mlc) expression. [More information is available at EcoGene: EG13377]. MtfA interacts with the transcriptional repressor Mlc and thus modulates the expression of genes which are regulated by Mlc . [More information is available at EcoCyc: G7063].
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Genomic context

Sequence:
NC_000913.3 (2043651..2044448)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative cytochrome b561 YodB Neighboring gene tRNA-Ser Neighboring gene tRNA-Asn Neighboring gene inverse autotransporter adhesin

Interactions

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aminopeptidase activity  
enables aminopeptidase activity PubMed 
enables aminopeptidase activity  
enables metal ion binding  
enables metallopeptidase activity  
enables protein binding PubMed 
enables zinc ion binding  
Process Evidence Code Pubs
involved_in proteolysis  
Component Evidence Code Pubs
located_in cytoplasm  
is_active_in cytosol  
located_in cytosol PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2043651..2044448
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416484.2 Mlc titration factor [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416484.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A403D3B4
    Conserved Domains (1) summary
    PRK15410
    Location:1260
    PRK15410; DgsA anti-repressor MtfA; Provisional
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