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setB sugar exporter SetB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946673, updated on 17-Dec-2024

Summary

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Official Symbol
setB
Official Full Name
sugar exporter SetB
Primary source
ECOCYC:EG12034
Locus tag
b2170
See related
ASAP:ABE-0007184
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2163; yeiO
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG12034]. SetB is a probable efflux transporter for sugars such as lactose and IPTG. [More information is available at EcoCyc: EG12034].
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Genomic context

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Sequence:
NC_000913.3 (2263863..2265044)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 1-phosphofructokinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruB Neighboring gene putative metal-chelating domain-containing protein YeiW Neighboring gene elongation factor P-like protein YeiP Neighboring gene putative oxidoreductase YeiQ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The identification of a new family of sugar efflux pumps in Escherichia coli. Liu JY, et al. Mol Microbiol, 1999 Mar. PMID 10209755
  2. SetB: an integral membrane protein that affects chromosome segregation in Escherichia coli. Espeli O, et al. Mol Microbiol, 2003 Oct. PMID 14617174
  3. Functional and biochemical characterization of Escherichia coli sugar efflux transporters. Liu JY, et al. J Biol Chem, 1999 Aug 13. PMID 10438463
  4. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
  5. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate:proton symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables carbohydrate:proton symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-glucose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within D-glucose transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within carbohydrate transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within carbohydrate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to glucose-phosphate stress IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in lactose transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lactose transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sugar exporter SetB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2263863..2265044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416675.1 sugar exporter SetB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416675.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376FZB0, A0A8T5ZBQ8
    Conserved Domains (1) summary
    PRK15011
    Location:1 → 393
    PRK15011; sugar efflux transporter SetB
Nucleotide Protein
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