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mdtH multidrug efflux pump MdtH [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946920, updated on 3-Dec-2024

Summary

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Official Symbol
mdtH
Official Full Name
multidrug efflux pump MdtH
Primary source
ECOCYC:G6559
Locus tag
b1065
See related
ASAP:ABE-0003618
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1050; yceL
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13878]. The YceL protein is, based on sequence similarity and hydropathy analysis, a member of the major facilitator superfamily (MFS) . [More information is available at EcoCyc: G6559].
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Genomic context

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Sequence:
NC_000913.3 (1124118..1125326, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative lipid-binding lipoprotein YceB Neighboring gene reduced glutaredoxin 2 Neighboring gene ribosomal-protein-S5-alanine N-acetyltransferase Neighboring gene DUF480 domain-containing protein YceH

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli. Vlamis-Gardikas A, et al. J Biol Chem, 1997 Apr 25. PMID 9111025
  2. Microbial genome analyses: comparative transport capabilities in eighteen prokaryotes. Paulsen IT, et al. J Mol Biol, 2000 Aug 4. PMID 10926494
  3. Indole induces the expression of multidrug exporter genes in Escherichia coli. Hirakawa H, et al. Mol Microbiol, 2005 Feb. PMID 15686558
  4. Analysis of a complete library of putative drug transporter genes in Escherichia coli. Nishino K, et al. J Bacteriol, 2001 Oct. PMID 11566977, Free PMC Article
  5. Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12. Eydallin G, et al. FEBS Lett, 2007 Jun 26. PMID 17543954

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to antibiotic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
multidrug efflux pump MdtH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1124118..1125326 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415583.4 multidrug efflux pump MdtH [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415583.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3L5H8P4
    Conserved Domains (1) summary
    PRK11646
    Location:1 → 400
    PRK11646; multidrug efflux MFS transporter MdtH
Nucleotide Protein
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