U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

eutC ethanolamine ammonia-lyase subunit beta [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946925, updated on 17-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
eutC
Official Full Name
ethanolamine ammonia-lyase subunit beta
Primary source
ECOCYC:EG50007
Locus tag
b2440
See related
ASAP:ABE-0008043
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2435
Summary
EutBC deaminates amino-alcohols (ethanolamine) to oxo compounds (acetaldehyde) and ammonia. [More information is available at EcoGene: EG50007]. EutC codes for the smaller subunit, which is the probable catalytic subunit carrying the ethanolamine and adenosylcobalamin binding sites. [More information is available at EcoCyc: EG50007].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (2556410..2557297, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative structural protein, ethanolamine utilization microcompartment Neighboring gene putative structural protein, ethanolamine utilization microcompartment Neighboring gene ethanolamine ammonia-lyase subunit alpha Neighboring gene putative phage integrase IntZ

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Direct Participation of a Peripheral Side Chain of a Corrin Ring in Coenzyme B(12) Catalysis. Shibata N, et al. Angew Chem Int Ed Engl, 2018 Jun 25. PMID 29797764
  2. Microbial metabolism of amino alcohols. Purification and properties of coenzyme B12-dependent ethanolamine ammonia-lyase of Escherichia coli. Blackwell CM, et al. Biochem J, 1978 Nov 1. PMID 33657, Free PMC Article
  3. Microbial metabolism of amino alcohols. Control of formation and stability of partially purified ethanolamine ammonia-lyase in Escherichia coli. Blackwell CM, et al. J Gen Microbiol, 1977 Jan. PMID 319195
  4. Microbial metabolism of amino alcohols. Formation of coenzyme B12-dependent ethanolamine ammonia-lyase and its concerted induction in Escherichia coli. Blackwell CM, et al. Biochem J, 1978 Dec 15. PMID 371614, Free PMC Article
  5. A model for the common control of enzymes of ethanolamine catabolism in Escherichia coli. Jones PW, et al. J Gen Microbiol, 1984 Apr. PMID 6376700

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Cloning, sequencing, and expression of the genes encoding the adenosylcobalamin-dependent ethanolamine ammonia-lyase of Salmonella typhimurium.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cobalamin binding IEA
Inferred from Electronic Annotation
more info
  
enables ethanolamine ammonia-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ethanolamine catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in ethanolamine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in bacterial microcompartment IEA
Inferred from Electronic Annotation
more info
  
part_of ethanolamine ammonia-lyase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ethanolamine ammonia-lyase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ethanolamine ammonia-lyase complex IEA
Inferred from Electronic Annotation
more info
  
part_of ethanolamine ammonia-lyase complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of ethanolamine ammonia-lyase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in ethanolamine degradation polyhedral organelle IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ethanolamine ammonia-lyase subunit beta
NP_416935.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2556410..2557297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416935.1 ethanolamine ammonia-lyase subunit beta [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416935.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M4J9
    Conserved Domains (1) summary
    COG4302
    Location:1 → 295
    EutC; Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.