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rplS 50S ribosomal subunit protein L19 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947096, updated on 3-Dec-2024

Summary

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Official Symbol
rplS
Official Full Name
50S ribosomal subunit protein L19
Primary source
ECOCYC:EG10880
Locus tag
b2606
See related
ASAP:ABE-0008574
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2603
Summary
The L19 protein is a component of the 50S subunit of the ribosome. [More information is available at EcoCyc: EG10880].
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Genomic context

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Sequence:
NC_000913.3 (2744183..2744530, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF4154 domain-containing protein YfiR Neighboring gene diguanylate cyclase DgcN Neighboring gene lipoprotein YfiB Neighboring gene tRNA m(1)G37 methyltransferase Neighboring gene ribosome maturation factor RimM

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alterations in ribosomal protein L19 that decrease the fidelity of translation. VanNice J, et al. Biochimie, 2016 Sep-Oct. PMID 27477481, Free PMC Article
  2. Primary structure of protein L19 from the large subunit of Escherichia coli ribosomes. Brosius J, et al. Biochemistry, 1978 Feb 7. PMID 339951
  3. Proteins associated with rRNA in the Escherichia coli ribosome. Bernabeu C, et al. Biochim Biophys Acta, 1978 Apr 27. PMID 350280
  4. Non-autogenous control of ribosomal protein synthesis from the trmD operon in Escherichia coli. Wikström PM, et al. J Mol Biol, 1988 Sep 5. PMID 2460631
  5. Reversion from erythromycin dependence in Escherichia coli: strains altered in ribosomal sub-unit association and ribosome assembly. Wild DG. J Gen Microbiol, 1988 May. PMID 2462010

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that ribosomal protein L19 (rplS) mutants promote increased stop codon readthrough, but do not have major effects on subunit association or cell growth.
    Title: Alterations in ribosomal protein L19 that decrease the fidelity of translation.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: Primary structure of protein L19 from the large subunit of Escherichia coli ribosomes.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables large ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in ribosomal large subunit assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
50S ribosomal subunit protein L19

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2744183..2744530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417097.1 50S ribosomal subunit protein L19 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417097.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376Y497
    Conserved Domains (1) summary
    PRK05338
    Location:2 → 115
    rplS; 50S ribosomal protein L19; Provisional
Nucleotide Protein
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