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cysC adenylyl-sulfate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947221, updated on 3-Dec-2024

Summary

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Official Symbol
cysC
Official Full Name
adenylyl-sulfate kinase
Primary source
ECOCYC:EG10185
Locus tag
b2750
See related
ASAP:ABE-0009023
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2745
Summary
The enzyme exists predominantly as a homodimer, but a tetrameric form exists when the enzyme is dephosphorylated. [More information is available at EcoCyc: EG10185].
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Genomic context

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Sequence:
NC_000913.3 (2873387..2873992, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cell division protein FtsB Neighboring gene DUF3561 domain-containing inner membrane protein YgbE Neighboring gene sulfate adenylyltransferase subunit 1 Neighboring gene sulfate adenylyltransferase subunit 2 Neighboring gene alkaline phosphatase isozyme conversion protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mechanistic studies of Escherichia coli adenosine-5'-phosphosulfate kinase. Satishchandran C, et al. Arch Biochem Biophys, 2000 Jun 15. PMID 10860538
  2. Adenosine-5'-phosphosulfate kinase from Escherichia coli K12. Purification, characterization, and identification of a phosphorylated enzyme intermediate. Satishchandran C, et al. J Biol Chem, 1989 Sep 5. PMID 2549047
  3. Characterization of the phosphorylated enzyme intermediate formed in the adenosine 5'-phosphosulfate kinase reaction. Satishchandran C, et al. Biochemistry, 1992 Dec 1. PMID 1332767
  4. Lambda transducing phage and clones carrying genes of the cysJIHDC gene cluster of Escherichia coli K12. Hunt CL, et al. J Gen Microbiol, 1987 Oct. PMID 2966849
  5. The DNA sequence of the sulfate activation locus from Escherichia coli K-12. Leyh TS, et al. J Biol Chem, 1992 May 25. PMID 1316900

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: The DNA sequence of the sulfate activation locus from Escherichia coli K-12.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables adenylylsulfate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables adenylylsulfate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables adenylylsulfate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in hydrogen sulfide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfate assimilation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sulfate assimilation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adenylyl-sulfate kinase
NP_417230.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2873387..2873992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417230.1 adenylyl-sulfate kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417230.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5ZGN1
    Conserved Domains (1) summary
    PRK03846
    Location:5 → 201
    PRK03846; adenylylsulfate kinase; Provisional
Nucleotide Protein
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