U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

qmcA PHB domain-containing protein QmcA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947257, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
qmcA
Official Full Name
PHB domain-containing protein QmcA
Primary source
ECOCYC:G6265
Locus tag
b0489
See related
ASAP:ABE-0001697
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0483; ybbK
Summary
Prohibitin homology (PHB) domain. [More information is available at EcoGene: EG13258]. qmcA can act as a multicopy suppressor of a ftsH htpX double disruption mutant, though the gene is nonessential at normal growth conditions. [More information is available at EcoCyc: G6265].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (514856..515773, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YbaT Neighboring gene DNA-binding transcriptional dual regulator CueR Neighboring gene NfeD-like family protein YbbJ Neighboring gene putative iron ABC exporter ATP-binding subunit FetA Neighboring gene putative iron ABC exporter membrane subunit FetB Neighboring gene chaperedoxin

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Ancient origin of reggie (flotillin), reggie-like, and other lipid-raft proteins: convergent evolution of the SPFH domain. Rivera-Milla E, et al. Cell Mol Life Sci, 2006 Feb. PMID 16389450, Free PMC Article
  2. Quality control of cytoplasmic membrane proteins in Escherichia coli. Akiyama Y. J Biochem, 2009 Oct. PMID 19454621
  3. Evolution of prokaryotic SPFH proteins. Hinderhofer M, et al. BMC Evol Biol, 2009 Jan 12. PMID 19138386, Free PMC Article
  4. Eukaryotic and prokaryotic stomatins: the proteolytic link. Green JB, et al. Blood Cells Mol Dis, 2004 May-Jun. PMID 15121101
  5. The Escherichia coli plasma membrane contains two PHB (prohibitin homology) domain protein complexes of opposite orientations. Chiba S, et al. Mol Microbiol, 2006 Apr. PMID 16573693

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
PHB domain-containing protein QmcA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    514856..515773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415022.1 PHB domain-containing protein QmcA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415022.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6M9QUN8
    Conserved Domains (1) summary
    COG0330
    Location:1 → 293
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.