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gudX glucarate dehydratase-related protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947261, updated on 3-Dec-2024

Summary

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Official Symbol
gudX
Official Full Name
glucarate dehydratase-related protein
Primary source
ECOCYC:G7446
Locus tag
b2788
See related
ASAP:ABE-0009136
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2782; ygcY
Summary
GudX (GlucD-related protein, GlucDRP) has similarity to the functional D-glucarate dehydratase, GudD, which is encoded in a probable operon downstream of gudX. [More information is available at EcoCyc: G7446].
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Genomic context

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Sequence:
NC_000913.3 (2919406..2920746, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sensor histidine kinase BarA Neighboring gene D-glucarate dehydratase Neighboring gene galactarate/D-glucarate transporter GudP Neighboring gene putative flavodoxin YqcA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. Monterrubio R, et al. J Bacteriol, 2000 May. PMID 10762278, Free PMC Article
  2. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Hubbard BK, et al. Biochemistry, 1998 Oct 13. PMID 9772162
  3. Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity. Gerlt JA, et al. Arch Biochem Biophys, 2005 Jan 1. PMID 15581566
  4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables glucarate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-glucarate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
glucarate dehydratase-related protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2919406..2920746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417268.1 glucarate dehydratase-related protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417268.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376FXD6
    Conserved Domains (1) summary
    cd03323
    Location:8 → 416
    D-glucarate_dehydratase; D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes, ...
Nucleotide Protein
Heading Accession and Version

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