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mtr tryptophan:H(+) symporter Mtr [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947675, updated on 3-Dec-2024

Summary

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Official Symbol
mtr
Official Full Name
tryptophan:H(+) symporter Mtr
Primary source
ECOCYC:EG10617
Locus tag
b3161
See related
ASAP:ABE-0010387
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3149
Summary
TyrR regulon. [More information is available at EcoGene: EG10617]. Mtr is one of three known transporters for tryptophan in Escherichia coli, the others being TnaB and AroP. [More information is available at EcoCyc: EG10617].
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Genomic context

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Sequence:
NC_000913.3 (3304573..3305817, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ubiquinone biosynthesis protein UbiV Neighboring gene putative luciferase-like monooxygenase YhbW Neighboring gene ATP-dependent RNA helicase DeaD Neighboring gene uncharacterized protein YrbN Neighboring gene lipoprotein NlpI

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Membrane topology analysis of Escherichia coli K-12 Mtr permease by alkaline phosphatase and beta-galactosidase fusions. Sarsero JP, et al. J Bacteriol, 1995 Jan. PMID 7814318, Free PMC Article
  2. 5-methyltryptophan-resistant mutations lniked with the arginine G marker in Escherichia coli. Hiraga S, et al. J Bacteriol, 1968 Nov. PMID 4882032, Free PMC Article
  3. The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12. Heatwole VM, et al. J Bacteriol, 1991 Jun. PMID 1904443, Free PMC Article
  4. Formation of aromatic amino acid pools in Escherichia coli K-12. Brown KD. J Bacteriol, 1970 Oct. PMID 4919744, Free PMC Article
  5. Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12. Heatwole VM, et al. J Bacteriol, 1991 Jan. PMID 1987112, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-tryptophan transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables aromatic amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in tryptophan transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tryptophan:H(+) symporter Mtr

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3304573..3305817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417630.1 tryptophan:H(+) symporter Mtr [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417630.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377DAG2
    Conserved Domains (1) summary
    PRK10483
    Location:1 → 414
    PRK10483; tryptophan permease; Provisional
Nucleotide Protein
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