rbfA 30S ribosome binding factor [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: rbfA
Official Full Name: 30S ribosome binding factor
Primary source: ECOCYC:EG11178
Locus tag: b3167
See related: ASAP:ABE-0010406
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK3156; sdr-43; yhbB
Summary: RbfA can be found associated with the 30S subunit of the ribosome and is essential for efficient processing of the 16S rRNA . [More information is available at EcoCyc: EG11178].
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NC_000913.3 Genomic Context describing neighboring genes

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An Alternative Role of RluD in the Fidelity of Translation Initiation in Escherichia coli.
Title: An Alternative Role of RluD in the Fidelity of Translation Initiation in Escherichia coli.
By gating the transition from 30S ribosome biogenesis to translation initiation, RbfA and IF3 maintain the fidelity of bacterial protein synthesis.
Title: RbfA and IF3 couple ribosome biogenesis and translation initiation to increase stress tolerance.
Results shows that YjeQ promotes the release of RbfA through the C-terminal helix in its zinc-finger domain.
Title: The C-terminal helix in the YjeQ zinc-finger domain catalyzes the release of RbfA during 30S ribosome subunit assembly.
Overexpression of RbfA in the absence of the KsgA results in impaired translation initiation.
Title: Overexpression of RbfA in the absence of the KsgA checkpoint results in impaired translation initiation.
N-terminus verified by Edman degradation on mature peptide
Title: '98 Escherichia coli SWISS-2DPAGE database update.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ribosomal small subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribosomal small subunit binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maturation of SSU-rRNA	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within maturation of SSU-rRNA	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within maturation of SSU-rRNA	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to cold	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within ribosomal small subunit biogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within ribosomal small subunit biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ribosome biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IC Inferred by Curator more info	PubMed
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain