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prmA ribosomal protein L11 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947708, updated on 3-Dec-2024

Summary

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Official Symbol
prmA
Official Full Name
ribosomal protein L11 methyltransferase
Primary source
ECOCYC:EG11497
Locus tag
b3259
See related
ASAP:ABE-0010697
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3246; prm-1; yhdI
Summary
PrmA is the methyltransferase responsible for the multiple methylation of ribosomal protein L11. prmA mutants are deficient in the methylation of ribosomal protein L11 . [More information is available at EcoCyc: EG11497].
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Genomic context

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Sequence:
NC_000913.3 (3409070..3409951)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene biotin carboxylase Neighboring gene DUF997 domain-containing protein YhdT Neighboring gene pantothenate:Na(+) symporter Neighboring gene tRNA-dihydrouridine synthase B Neighboring gene DNA-binding transcriptional dual regulator Fis

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and properties of a ribosomal protein methylase from Eschericha coli Q13. Chang FN, et al. Biochemistry, 1975 Nov 4. PMID 241395
  2. Genetics of ribosomal protein methylation in Escherichia coli. I. A mutant deficient in methylation of protein L11. Colson C. Mol Gen Genet, 1977 Jul 20. PMID 331082
  3. Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases. Bujnicki JM. Acta Microbiol Pol, 2000. PMID 10997488
  4. N-Trimethylalanine, a novel blocking group, found in E. coli ribosomal protein L11. Lederer F, et al. Biochem Biophys Res Commun, 1977 Jul 25. PMID 332162
  5. Genetics of ribosomal protein methylation in Escherichia coli. III. Map position of two genes, prmA and prmB, governing methylation of proteins L11 and L3. Colson C, et al. Mol Gen Genet, 1979 Feb 1. PMID 372746

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
    Title: Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables N-terminal protein N-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables histone methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-lysine N-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-lysine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ribosomal protein L11 methyltransferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3409070..3409951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417725.1 ribosomal protein L11 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417725.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6QD37
    Conserved Domains (1) summary
    TIGR00406
    Location:3 → 286
    prmA; ribosomal protein L11 methyltransferase
Nucleotide Protein
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