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cysG siroheme synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947880, updated on 3-Dec-2024

Summary

Official Symbol
cysG
Official Full Name
siroheme synthase
Primary source
ECOCYC:EG10188
Locus tag
b3368
See related
ASAP:ABE-0011010
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3356
Summary
YraL is homologous to the C-terminal methyltransferase domain of CysG. cysG is transcribed from the nirB operon and from cysG promoters. [More information is available at EcoGene: EG10188]. The Escherichia coli |FRAME: [More information is available at EcoCyc: EG10188].
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Genomic context

Sequence:
NC_000913.3 (3497828..3499201)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene nitrite reductase (NADH) large subunit Neighboring gene nitrite reductase (NADH) small subunit Neighboring gene nitrite transporter NirC Neighboring gene DUF4223 domain-containing lipoprotein YhfL Neighboring gene fructoselysine/psicoselysine transporter

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 
enables ferrochelatase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables precorrin-2 dehydrogenase activity EXP
Inferred from Experiment
more info
PubMed 
enables precorrin-2 dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
enables sirohydrochlorin ferrochelatase activity EXP
Inferred from Experiment
more info
PubMed 
enables sirohydrochlorin ferrochelatase activity IEA
Inferred from Electronic Annotation
more info
 
enables uroporphyrin-III C-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables uroporphyrin-III C-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables uroporphyrin-III C-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cobalamin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in porphyrin-containing compound biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within siroheme biosynthetic process EXP
Inferred from Experiment
more info
PubMed 
involved_in siroheme biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in siroheme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3497828..3499201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417827.1 siroheme synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417827.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3P5DV28, A0A8S7EAT8
    Conserved Domains (1) summary
    PRK10637
    Location:1457
    cysG; siroheme synthase CysG