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livF branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947961, updated on 3-Dec-2024

Summary

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Official Symbol
livF
Official Full Name
branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
Primary source
ECOCYC:EG10536
Locus tag
b3454
See related
ASAP:ABE-0011282
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3438
Summary
LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10536].
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Genomic context

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Sequence:
NC_000913.3 (3592724..3593437, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753
  2. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article
  3. Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli. Haney SA, et al. J Bacteriol, 1992 Jan. PMID 1729203, Free PMC Article
  4. The LIV-I/LS system as a determinant of azaserine sensitivity of Escherichia coli K-12. Koyanagi T, et al. FEMS Microbiol Lett, 2004 Aug 1. PMID 15268940
  5. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables L-isoleucine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-leucine transmembrane transporter activity EXP
Inferred from Experiment
more info
 PubMed 
contributes_to L-leucine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-valine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-valine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within branched-chain amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in branched-chain amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in branched-chain amino acid transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within isoleucine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within phenylalanine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phenylalanine transport NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
NP_417911.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3592724..3593437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417911.4 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417911.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X1MQ44
    Conserved Domains (1) summary
    PRK11614
    Location:1 → 237
    livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF
Nucleotide Protein
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