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rbbA ribosome-associated ATPase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947998, updated on 3-Dec-2024

Summary

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Official Symbol
rbbA
Official Full Name
ribosome-associated ATPase
Primary source
ECOCYC:EG12223
Locus tag
b3486
See related
ASAP:ABE-0011381
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3471; yhiG; yhiH
Summary
RbbA is homologous to the ABC-type transporter family, but has no overexpression resistance phenotype and is not a membrane transporter. [More information is available at EcoGene: EG12223]. RbbA is associated with the 30S subunit of the ribosome and has ribosome-dependent ATPase activity . [More information is available at EcoCyc: EG12223].
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Genomic context

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Sequence:
NC_000913.3 (3626803..3629538, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transposase Neighboring gene ABC transporter family protein YhhJ Neighboring gene putative membrane fusion protein YhiI Neighboring gene protein YhiY Neighboring gene DUF4049 domain-containing protein YhiJ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes. Xu J, et al. Nucleic Acids Res, 2006. PMID 16495476, Free PMC Article
  2. Isolation and point of action of a factor from Escherichia coli required to reconstruct translation. Ganoza MC, et al. Proc Natl Acad Sci U S A, 1985 Mar. PMID 3885216, Free PMC Article
  3. Requirements for in vitro reconstruction of protein synthesis. Green RH, et al. Biochem Biophys Res Commun, 1985 Jan 31. PMID 3884000
  4. A new factor from Escherichia coli affects translocation of mRNA. Ganoza MC, et al. J Biol Chem, 1995 Nov 3. PMID 7592851
  5. A ribosomal ATPase is a target for hygromycin B inhibition on Escherichia coli ribosomes. Ganoza MC, et al. Antimicrob Agents Chemother, 2001 Oct. PMID 11557474, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A truncated form of the RbbA protein binds at the E-site of ribosomes.
    Title: Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ribosomal small subunit binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of translation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell pole IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosome-associated ATPase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3626803..3629538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026225.1 ribosome-associated ATPase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026225.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376FVK4
    Conserved Domains (1) summary
    NF033858
    Location:12 → 910
    ABC2_perm_RbbA; ribosome-associated ATPase/putative transporter RbbA
Nucleotide Protein
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