U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gor glutathione reductase (NADPH) [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948014, updated on 3-Dec-2024

Summary

Official Symbol
gor
Official Full Name
glutathione reductase (NADPH)
Primary source
ECOCYC:EG10412
Locus tag
b3500
See related
ASAP:ABE-0011432
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3485; gorA
Summary
Glutathione reductase is a member of the flavin-containing NADPH:disulfide oxidoreductases (DSOR) family. [More information is available at EcoCyc: EG10412].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3646299..3647651)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene oligopeptidase A Neighboring gene 23S rRNA m(6)A2030 methyltransferase Neighboring gene membrane toxin DinQ Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables FAD binding IDA
Inferred from Direct Assay
more info
PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables glutathione-disulfide reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glutathione-disulfide reductase (NADPH) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables glutathione-disulfide reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell redox homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane HDA PubMed 

General protein information

Preferred Names
glutathione reductase (NADPH)
NP_417957.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3646299..3647651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417957.1 glutathione reductase (NADPH) [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417957.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6D0IIW4
    Conserved Domains (1) summary
    PRK06116
    Location:1450
    PRK06116; glutathione reductase; Validated