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dppA dipeptide ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948062, updated on 17-Dec-2024

Summary

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Official Symbol
dppA
Official Full Name
dipeptide ABC transporter periplasmic binding protein
Primary source
ECOCYC:EG10248
Locus tag
b3544
See related
ASAP:ABE-0011576
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
alu; dpp; ECK3531; fpp
Summary
DppA binds dipeptides and heme, and mediates chemotaxis to dipeptides through the Tap chemoreceptor. [More information is available at EcoGene: EG10248]. DppA is the periplasmic binding component of the dipeptide ABC transporter. [More information is available at EcoCyc: EG10248].
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Genomic context

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Sequence:
NC_000913.3 (3706098..3707705, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene dipeptide ABC transporter membrane subunit DppC Neighboring gene dipeptide ABC transporter membrane subunit DppB Neighboring gene tRNA-Pro Neighboring gene phosphoethanolamine transferase EptB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enzymatic degradation and transport of endothiopeptides into Escherichia coli K12 mutant strains. Nowak-Jary J, et al. FEMS Microbiol Lett, 2008 Aug. PMID 18557941
  2. The role of the small regulatory RNA GcvB in GcvB/mRNA posttranscriptional regulation of oppA and dppA in Escherichia coli. Pulvermacher SC, et al. FEMS Microbiol Lett, 2008 Apr. PMID 18312576
  3. Role of the Escherichia coli Hfq protein in GcvB regulation of oppA and dppA mRNAs. Pulvermacher SC, et al. Microbiology (Reading), 2009 Jan. PMID 19118352
  4. Protein patterns of gel-entrapped Escherichia coli cells differ from those of free-floating organisms. Perrot F, et al. Electrophoresis, 2000 Feb. PMID 10726772
  5. Direct determination of the properties of peptide transport systems in Escherichia coli, using a fluorescent-labeling procedure. Payne JW, et al. J Bacteriol, 1979 Jan. PMID 368023, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables dipeptide transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables dipeptide transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables heme binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables peptide binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chaperone-mediated protein folding IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
  
involved_in dipeptide transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in dipeptide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dipeptide transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within dipeptide transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in dipeptide transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in heme transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within heme transport EXP
Inferred from Experiment
more info
 PubMed 
involved_in peptide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptide transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive chemotaxis EXP
Inferred from Experiment
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in outer membrane-bounded periplasmic space EXP
Inferred from Experiment
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dipeptide ABC transporter periplasmic binding protein
NP_418001.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3706098..3707705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418001.1 dipeptide ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418001.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN5UHY5
    Conserved Domains (1) summary
    cd08493
    Location:30 → 519
    PBP2_DppA_like; The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold
Nucleotide Protein
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