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ligB DNA ligase B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948164, updated on 3-Dec-2024

Summary

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Official Symbol
ligB
Official Full Name
DNA ligase B
Primary source
ECOCYC:EG11334
Locus tag
b3647
See related
ASAP:ABE-0011923
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3637; yicF
Summary
LigB is a NAD(+)-dependent DNA ligase . [More information is available at EcoCyc: EG11334].
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Genomic context

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Sequence:
NC_000913.3 (3819488..3821170, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative RNase adaptor protein YicC Neighboring gene DNA damage-inducible protein D Neighboring gene PF03458 family inner membrane protein YicG Neighboring gene guanylate kinase Neighboring gene RNA polymerase subunit omega

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Escherichia coli DNA ligase B may mitigate damage from oxidative stress. Bodine TJ, et al. PLoS One, 2017. PMID 28700629, Free PMC Article
  2. Guanylate kinase of Escherichia coli K-12. Gentry D, et al. J Biol Chem, 1993 Jul 5. PMID 8390989
  3. DNA and RNA ligases: structural variations and shared mechanisms. Pascal JM. Curr Opin Struct Biol, 2008 Feb. PMID 18262407
  4. The majority of Escherichia coli mRNAs undergo post-transcriptional modification in exponentially growing cells. Mohanty BK, et al. Nucleic Acids Res, 2006. PMID 17040898, Free PMC Article
  5. DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication. Burland V, et al. Genomics, 1993 Jun. PMID 7686882

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA ligase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA ligase (NAD+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA ligase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA ligation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in DNA ligation involved in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within DNA ligation involved in DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in DNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA ligase B
NP_418104.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3819488..3821170 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418104.2 DNA ligase B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418104.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3JA95
    Conserved Domains (1) summary
    PRK08097
    Location:1 → 560
    ligB; NAD-dependent DNA ligase LigB
Nucleotide Protein
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