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uhpA DNA-binding transcriptional activator UhpA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948178, updated on 3-Dec-2024

Summary

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Official Symbol
uhpA
Official Full Name
DNA-binding transcriptional activator UhpA
Primary source
ECOCYC:EG11051
Locus tag
b3669
See related
ASAP:ABE-0011995
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3660
Summary
Transcriptional regulatory protein UhpA belongs to the two-component regulatory system UhpB/UhpA. [More information is available at EcoCyc: EG11051].
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Genomic context

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Sequence:
NC_000913.3 (3850136..3850726, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hexose-6-phosphate:phosphate antiporter Neighboring gene inner membrane protein sensing glucose-6-phosphate Neighboring gene sensory histidine kinase UhpB Neighboring gene acetohydroxy acid synthase I subunit IlvN Neighboring gene acetohydroxy acid synthase I subunit IlvB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Frequency and Mechanisms of Spontaneous Fosfomycin Nonsusceptibility Observed upon Disk Diffusion Testing of Escherichia coli. Lucas AE, et al. J Clin Microbiol, 2018 Jan. PMID 29093108, Free PMC Article
  2. Protein phosphorylation affects binding of the Escherichia coli transcription activator UhpA to the uhpT promoter. Dahl JL, et al. J Biol Chem, 1997 Jan 17. PMID 8999880
  3. Involvement of the amino-terminal phosphorylation module of UhpA in activation of uhpT transcription in Escherichia coli. Webber CA, et al. Mol Microbiol, 1997 Jun. PMID 9220010
  4. Separate contributions of UhpA and CAP to activation of transcription of the uhpT promoter of Escherichia coli. Olekhnovich IN, et al. J Mol Biol, 1999 Oct 8. PMID 10512697
  5. Effect of altered spacing between uhpT promoter elements on transcription activation. Chen Q, et al. J Bacteriol, 2000 Aug. PMID 10913075, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional activator UhpA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3850136..3850726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418125.1 DNA-binding transcriptional activator UhpA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418125.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YNM7
    Conserved Domains (1) summary
    PRK10360
    Location:1 → 196
    PRK10360; transcriptional regulator UhpA
Nucleotide Protein
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