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frwB putative PTS enzyme IIB component FrwB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948447, updated on 3-Dec-2024

Summary

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Official Symbol
frwB
Official Full Name
putative PTS enzyme IIB component FrwB
Primary source
ECOCYC:EG11909
Locus tag
b3950
See related
ASAP:ABE-0012930
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3941; yijK
Summary
FrwCBD PtsA, a putative PTS permease, belongs to the functional superfamily of the phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). [More information is available at EcoCyc: EG11909].
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Genomic context

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Sequence:
NC_000913.3 (4143624..4143944)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS multiphosphoryl transfer protein PtsA Neighboring gene putative PTS enzyme IIC component FrwC Neighboring gene putative formate acetyltransferase 2 Neighboring gene putative pyruvate formate-lyase 2 activating enzyme PflC Neighboring gene putative PTS enzyme IIB component FrwD Neighboring gene putative DNA-binding transcriptional regulator YijO

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
  2. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
  3. Large-scale identification of protein-protein interaction of Escherichia coli K-12. Arifuzzaman M, et al. Genome Res, 2006 May. PMID 16606699, Free PMC Article
  4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
  5. Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Postma PW, et al. Microbiol Rev, 1993 Sep. PMID 8246840, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in fructose import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of transmembrane transporter complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
putative PTS enzyme IIB component FrwB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4143624..4143944
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418385.1 putative PTS enzyme IIB component FrwB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418385.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S0FGX8
    Conserved Domains (1) summary
    COG1445
    Location:1 → 103
    FrwB; Phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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