U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gltP glutamate/aspartate : H(+) symporter GltP [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948591, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
gltP
Official Full Name
glutamate/aspartate : H(+) symporter GltP
Primary source
ECOCYC:EG10405
Locus tag
b4077
See related
ASAP:ABE-0013357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4070
Summary
Escherichia coli contains four transporters for the uptake of glutamate (GltIJKL, GltP, GltS, and GadC) and five transporters for the uptake of aspartate (GltIJKL, GltP, DctA, DcuA, and DcuB). [More information is available at EcoCyc: EG10405].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (4294481..4295794)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative cytochrome c-type biogenesis protein NrfE Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG Neighboring gene Sel1 repeat-containing protein YjcO Neighboring gene formate dehydrogenase H

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Revised nucleotide sequence of the gltP gene, which encodes the proton-glutamate-aspartate transport protein of Escherichia coli K-12. Tolner B, et al. J Bacteriol, 1992 Apr. PMID 1551855, Free PMC Article
  2. Cloning and sequencing of a gene encoding a glutamate and aspartate carrier of Escherichia coli K-12. Wallace B, et al. J Bacteriol, 1990 Jun. PMID 1971622, Free PMC Article
  3. Calcium channel subtypes in rat brain: biochemical characterization of the high-affinity receptors for omega-conopeptides SNX-230 (synthetic MVIIC), SNX-183 (SVIB), and SNX-111 (MVIIA). Woppmann A, et al. Mol Cell Neurosci, 1994 Aug. PMID 7804605
  4. Location of the gltP gene on the physical map of Escherichia coli K-12. Lum D, et al. J Bacteriol, 1993 Sep. PMID 8366064, Free PMC Article
  5. Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii. Raunser S, et al. Biochemistry, 2006 Oct 24. PMID 17042498

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables amino acid:proton symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in carboxylic acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in dicarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dicarboxylic acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within dicarboxylic acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
glutamate/aspartate : H(+) symporter GltP

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4294481..4295794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418501.1 glutamate/aspartate : H(+) symporter GltP [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418501.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2H4TRW6, A0A376VTQ6, A0A5B9AM23
    Conserved Domains (1) summary
    PRK11283
    Location:1 → 437
    gltP; glutamate/aspartate:proton symporter; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.