U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ulaG L-ascorbate-6-phosphate lactonase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948705, updated on 17-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
ulaG
Official Full Name
L-ascorbate-6-phosphate lactonase
Primary source
ECOCYC:G7855
Locus tag
b4192
See related
ASAP:ABE-0013717
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4188; yjfR
Summary
UlaG has phosphodiesterase activity with model substrate bis-pNPPAFMB (Kuznetsova, 2005). [More information is available at EcoGene: EG12492]. UlaG is required for the ability to utilize L-ascorbate as the sole carbon source under anaerobic growth conditions. [More information is available at EcoCyc: G7855].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (4418561..4419625, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1471 domain-containing putative lipoprotein BsmA Neighboring gene carboxylesterase Neighboring gene DNA-binding transcriptional repressor UlaR Neighboring gene L-ascorbate specific PTS enzyme IIC component Neighboring gene L-ascorbate specific PTS enzyme IIB component

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular architecture of the Mn2+-dependent lactonase UlaG reveals an RNase-like metallo-beta-lactamase fold and a novel quaternary structure. Garces F, et al. J Mol Biol, 2010 May 21. PMID 20359483
  2. Overproduction, crystallization and preliminary X-ray analysis of the putative L-ascorbate-6-phosphate lactonase UlaG from Escherichia coli. Garces F, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Jan 1. PMID 18097099, Free PMC Article
  3. Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals. Huerta AM, et al. J Mol Biol, 2003 Oct 17. PMID 14529615
  4. Novel ligands for the extracellular solute receptors of two bacterial TRAP transporters. Thomas GH, et al. Microbiology (Reading), 2006 Jan. PMID 16385129
  5. The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli. Campos E, et al. J Bacteriol, 2002 Nov. PMID 12374842, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-ascorbate 6-phosphate lactonase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-ascorbate 6-phosphate lactonase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables manganese ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-ascorbic acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within L-ascorbic acid catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
L-ascorbate-6-phosphate lactonase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4418561..4419625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418613.2 L-ascorbate-6-phosphate lactonase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418613.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3HXW1, A0A1X3J7B2, A0A5B9ALW8, A0A829L917, A0AAJ3TZ42, A0AAN3MA83, C3SFU7
    Conserved Domains (1) summary
    PRK11709
    Location:1 → 354
    PRK11709; putative L-ascorbate 6-phosphate lactonase; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.