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ttcA tRNA cytosine(32) 2-sulfurtransferase TtcA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948967, updated on 17-Dec-2024

Summary

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Official Symbol
ttcA
Official Full Name
tRNA cytosine(32) 2-sulfurtransferase TtcA
Primary source
ECOCYC:G6675
Locus tag
b1344
See related
ASAP:ABE-0004514
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1341; ydaO
Summary
The attachment site of Rac is a 26 bp repeat region flanking Rac: [More information is available at EcoGene: EG13357]. tRNA from a ttcA mutant lacks a component suggested to be s2C . [More information is available at EcoCyc: G6675].
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Genomic context

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Sequence:
NC_000913.3 (1411013..1411948, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YnaL Neighboring gene ATP-dependent RNA helicase DbpA Neighboring gene putative integrase Neighboring gene excisionase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TtcA a new tRNA-thioltransferase with an Fe-S cluster. Bouvier D, et al. Nucleic Acids Res, 2014 Jul. PMID 24914049, Free PMC Article
  2. The methyl group of the N6-methyl-N6-threonylcarbamoyladenosine in tRNA of Escherichia coli modestly improves the efficiency of the tRNA. Qian Q, et al. J Bacteriol, 1998 Apr. PMID 9537379, Free PMC Article
  3. Analysis of products of the Escherichia coli genomic genes and regulation of their expressions: an applicable procedure for genomic analysis of other microorganisms. Talukder AA, et al. Biosci Biotechnol Biochem, 1994 Jan. PMID 7764507
  4. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Ericsson UB, et al. Anal Biochem, 2006 Oct 15. PMID 16962548
  5. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sulfurtransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sulfurtransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sulfurtransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA modification IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA modification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA thio-modification IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tRNA thio-modification IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in tRNA thio-modification IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
tRNA cytosine(32) 2-sulfurtransferase TtcA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1411013..1411948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415860.1 tRNA cytosine(32) 2-sulfurtransferase TtcA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415860.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376JZ47
    Conserved Domains (1) summary
    PRK10696
    Location:11 → 268
    PRK10696; tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional
Nucleotide Protein
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