U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cho excinuclease Cho [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948996, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
cho
Official Full Name
excinuclease Cho
Primary source
ECOCYC:G6937
Locus tag
b1741
See related
ASAP:ABE-0005807
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1739; ydjQ
Summary
Homologous to N-terminal domain of UvrC. [More information is available at EcoGene: EG13993]. Cho is a DNA repair endonuclease that acts together with UvrC in incision repair of some DNA lesions . [More information is available at EcoCyc: G6937].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (1823515..1824402)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene osmotically-inducible lipoprotein OsmE Neighboring gene NH3-dependent NAD(+) synthetase Neighboring gene HutD family protein Ves Neighboring gene ATP-independent periplasmic chaperone Neighboring gene succinylglutamate desuccinylase Neighboring gene N-succinylarginine dihydrolase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cho Endonuclease Functions during DNA Interstrand Cross-Link Repair in Escherichia coli. Perera AV, et al. J Bacteriol, 2016 Nov 15. PMID 27573016, Free PMC Article
  2. A cut above: discovery of an alternative excision repair pathway in bacteria. Van Houten B, et al. Proc Natl Acad Sci U S A, 2002 Mar 5. PMID 11880612, Free PMC Article
  3. Cho, a second endonuclease involved in Escherichia coli nucleotide excision repair. Moolenaar GF, et al. Proc Natl Acad Sci U S A, 2002 Feb 5. PMID 11818552, Free PMC Article
  4. Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli. Lewis LK, et al. J Mol Biol, 1994 Aug 26. PMID 8057377
  5. Genetic analysis of repair and damage tolerance mechanisms for DNA-protein cross-links in Escherichia coli. Salem AM, et al. J Bacteriol, 2009 Sep. PMID 19617358, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in SOS response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within SOS response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in nucleotide-excision repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of excinuclease repair complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
excinuclease Cho

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1823515..1824402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416255.1 excinuclease Cho [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416255.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7H9S8J1
    Conserved Domains (1) summary
    PRK10545
    Location:1 → 286
    PRK10545; excinuclease Cho
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.