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secA preprotein translocase subunit SecA [ Escherichia coli O157:H7 str. EDL933 ]

Gene ID: 956789, discontinued on 20-May-2015
  • This record was discontinued.

Summary

Gene symbol
secA
Gene description
preprotein translocase subunit SecA
Locus tag
Z0108
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli O157:H7 str. EDL933 (strain: EDL933, serotype: O157:H7)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
Also known as
azi; div
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General protein information

Names
preprotein translocase subunit SecA
NP_285794.1
  • functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002655.2 Reference assembly

    Range
    112885..115590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_285794.1 preprotein translocase subunit SecA [Escherichia coli O157:H7 str. EDL933]

    Status: REVIEWED