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    Snrpg small nuclear ribonucleoprotein polypeptide G [ Mus musculus (house mouse) ]

    Gene ID: 68011, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Snrpgprovided by MGI
    Official Full Name
    small nuclear ribonucleoprotein polypeptide Gprovided by MGI
    Primary source
    MGI:MGI:1915261
    See related
    Ensembl:ENSMUSG00000057278 AllianceGenome:MGI:1915261
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SMG; sm-G; snRNP-G; 2810024K17Rik
    Summary
    Predicted to enable U1 snRNP binding activity. Predicted to contribute to RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of several cellular components, including methylosome; small nuclear ribonucleoprotein complex; and spliceosomal complex. Predicted to be active in P granule. Is expressed in several structures, including nervous system; oocyte; renal cortex; sensory organ; and thymus primordium. Orthologous to human SNRPG (small nuclear ribonucleoprotein polypeptide G). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 172.5), liver E14 (RPKM 152.1) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Snrpg in Genome Data Viewer
    Location:
    6 D1; 6 37.69 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (86348522..86355884)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (86371540..86378902)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene katanin p80 (WD40-containing) subunit B 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2792 Neighboring gene family with sequence similarity 136, member A Neighboring gene STARR-positive B cell enhancer ABC_E4839 Neighboring gene predicted gene, 52865 Neighboring gene prenylcysteine oxidase 1 Neighboring gene STARR-positive B cell enhancer ABC_E11322

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Relationship of quantitative reverse transcription polymerase chain reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome identifies mouse preimplantation embryo reference genes†. Tscherner AK, et al. Biol Reprod, 2023 Nov 15. PMID 37669129, Free PMC Article
    2. RNA binding proteins co-localize with small tau inclusions in tauopathy. Maziuk BF, et al. Acta Neuropathol Commun, 2018 Aug 1. PMID 30068389, Free PMC Article
    3. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article
    4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    5. The central role of EED in the orchestration of polycomb group complexes. Cao Q, et al. Nat Commun, 2014. PMID 24457600, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables U1 snRNP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables U1 snRNP binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spliceosomal snRNP assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in P granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SMN-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of SMN-Sm protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U1 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U12-type spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U2-type catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U2-type precatalytic spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U2-type spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4 snRNP ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U4 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U7 snRNP ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of U7 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of methylosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of methylosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    small nuclear ribonucleoprotein G
    Names
    sm protein G
    NP_080782.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026506.2 → NP_080782.1  small nuclear ribonucleoprotein G

      Status: PROVISIONAL

      Source sequence(s)
      AK013235
      Consensus CDS
      CCDS39541.1
      UniProtKB/Swiss-Prot
      P62309, Q52KC7
      Related
      ENSMUSP00000086987.6, ENSMUST00000089558.7
      Conserved Domains (1) summary
      cd01719
      Location:5 → 74
      Sm_G; Sm protein G

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      86348522..86355884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62309.1 GenPept UniProtKB/Swiss-Prot:P62309

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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