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    CG12288 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35027, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12288provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032620
    Locus tag
    Dmel_CG12288
    See related
    AllianceGenome:FB:FBgn0032620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg12288; Dmel\CG12288; RBM34
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human RBM34 (RNA binding motif protein 34). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12288 in Genome Data Viewer
    Location:
    36B4-36B4; 2-53 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16900535..16902218, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16900535..16902218, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tweek Neighboring gene uncharacterized protein Neighboring gene Aminopeptidase P Neighboring gene long non-coding RNA:CR43053

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The TreadWheel: A Novel Apparatus to Measure Genetic Variation in Response to Gently Induced Exercise for Drosophila. Mendez S, et al. PLoS One, 2016. PMID 27736996, Free PMC Article
    2. Anterior repression of a Drosophila stripe enhancer requires three position-specific mechanisms. Andrioli LP, et al. Development, 2002 Nov. PMID 12397102
    3. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
    4. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
    5. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12288-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16900535..16902218 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135978.2 → NP_609822.1  uncharacterized protein Dmel_CG12288 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609822.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSG1, Q9VJG2
      Related
      FBpp0080510
      Conserved Domains (2) summary
      cd12394
      Location:155 → 237
      RRM1_RBM34; RNA recognition motif 1 in RNA-binding protein 34 (RBM34) and similar proteins
      cl17169
      Location:261 → 332
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSG1 Q8MSG1
    Q9VJG2 Q9VJG2

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