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    CG43055 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 12798556, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG43055provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262357
    Locus tag
    Dmel_CG43055
    See related
    AllianceGenome:FB:FBgn0262357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG43055; MB8.chr2L.pasa.5
    Summary
    Predicted to enable galactose binding activity and pattern recognition receptor activity. Predicted to be involved in induction of bacterial agglutination. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC6A (C-type lectin domain containing 6A); CLEC4D (C-type lectin domain family 4 member D); and CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG43055 in Genome Data Viewer
    Location:
    24F1-24F1; 2-12 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4411155..4411824)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4411155..4411824)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dim1 Neighboring gene transfer RNA:Tryptophan-CCA 2-1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila. Jiang MD, et al. Brain Res Bull, 2017 Jun. PMID 28625786
    2. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718
    3. Changes in Neuronal Signaling and Cell Stress Response Pathways are Associated with a Multigenic Response of Drosophila melanogaster to DDT Selection. Seong KM, et al. Genome Biol Evol, 2017 Dec 1. PMID 29211847, Free PMC Article
    4. First transcriptome profiling of D. melanogaster after development in a deep underground low radiation background laboratory. Zarubin M, et al. PLoS One, 2021. PMID 34351964, Free PMC Article
    5. Development of fly tolerance to consuming a high-protein diet requires physiological, metabolic and transcriptional changes. Yurkevych IS, et al. Biogerontology, 2020 Oct. PMID 32468146

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactose binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in induction of bacterial agglutination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG43055-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4411155..4411824
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258938.2 → NP_001245867.1  uncharacterized protein Dmel_CG43055 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245867.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NE79
      Conserved Domains (1) summary
      cd00037
      Location:49 → 167
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NE79 M9NE79

    Gene LinkOut

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