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    bug bunker gear [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36749, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bugprovided by FlyBase
    Official Full Name
    bunker gearprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034050
    Locus tag
    Dmel_CG8297
    See related
    AllianceGenome:FB:FBgn0034050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8297; Dmel\CG8297
    Summary
    Predicted to be involved in cilium assembly. Predicted to be active in cilium. Is expressed in adult head. Human ortholog(s) of this gene implicated in Meckel syndrome. Orthologous to human TXNDC15 (thioredoxin domain containing 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bug in Genome Data Viewer
    Location:
    52D2-52D2; 2-76 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15934825..15935938)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11822330..11823443)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene bedraggled Neighboring gene Death-associated inhibitor of apoptosis 2 Neighboring gene Myelodysplasia/myeloid leukemia factor Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 4aa1 Neighboring gene Cytochrome c oxidase subunit 6A-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bedraggled, a putative transporter, influences the tissue polarity complex during the R3/R4 fate decision in the Drosophila eye. Rawls AS, et al. Genetics, 2007 Sep. PMID 17890365, Free PMC Article
    2. The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. Huh JR, et al. J Biol Chem, 2007 Jan 19. PMID 17068333
    3. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
    4. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article
    5. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    bunker gear
    Names
    CG8297-PA
    bug-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15934825..15935938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137221.3 → NP_611065.1  bunker gear [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611065.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JXE1
      Related
      FBpp0086426
      Conserved Domains (1) summary
      cl00388
      Location:128 → 191
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JXE1 Q7JXE1

    Gene LinkOut

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