Tfip11 tuftelin interacting protein 11 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tfip11provided by RGD
Official Full Name: tuftelin interacting protein 11provided by RGD
Primary source: RGD:1311449
See related: EnsemblRapid:ENSRNOG00000000663 AllianceGenome:RGD:1311449
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable nucleic acid binding activity. Predicted to be involved in negative regulation of protein-containing complex assembly and spliceosomal complex disassembly. Predicted to be located in chromosome, telomeric region; extracellular matrix; and nuclear lumen. Predicted to be part of U2-type post-mRNA release spliceosomal complex and catalytic step 2 spliceosome. Orthologous to human TFIP11 (tuftelin interacting protein 11). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 65.5), Thymus (RPKM 64.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q16

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (49960025..49972257, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (44299619..44311851, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (50320820..50333052, complement)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

AW532199 (e-PCR)
- UniSTS:245563

Tfip11 (e-PCR), detects polymorphism
- UniSTS:479292

AA957943 (e-PCR)
- UniSTS:261744

MARC_7037-7038:992008225:1 (e-PCR)
- UniSTS:231297

MARC_7037-7038:996687489:1 (e-PCR)
- UniSTS:231297

AA957943 (e-PCR)
- UniSTS:248210

BI282368 (e-PCR)
- UniSTS:249783

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biomineral tissue development	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of protein-containing complex assembly	ISO Inferred from Sequence Orthology more info
involved_in spliceosomal complex disassembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in spliceosomal complex disassembly	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal complex disassembly	ISO Inferred from Sequence Orthology more info
involved_in spliceosomal complex disassembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of U2-type post-mRNA release spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type post-mRNA release spliceosomal complex	ISO Inferred from Sequence Orthology more info
part_of U2-type post-mRNA release spliceosomal complex	ISS Inferred from Sequence or Structural Similarity more info
part_of catalytic step 2 spliceosome	ISO Inferred from Sequence Orthology more info
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular matrix	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	ISO Inferred from Sequence Orthology more info
part_of spliceosomal complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: tuftelin-interacting protein 11

Names: STIP-1; septin and tuftelin-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008291.1 → NP_001008292.1 tuftelin-interacting protein 11

See identical proteins and their annotated locations for NP_001008292.1

Status: PROVISIONAL

Source sequence(s)

BC085809

UniProtKB/Swiss-Prot

Q5U2Y6

UniProtKB/TrEMBL

A0A8I6A3N9, A6J264

Related

ENSRNOP00000000828.3, ENSRNOT00000000828.6

Conserved Domains (3) summary

pfam01585
Location:149 → 193

G-patch; G-patch domain

pfam07842
Location:397 → 666

GCFC; GC-rich sequence DNA-binding factor-like protein

pfam12457
Location:18 → 104

TIP_N; Tuftelin interacting protein N terminal